TY - GEN AU - Hernández-Ledesma,Blanca AU - Martínez-Villaluenga,Cristina AU - Hernández-Ledesma,Blanca AU - Martínez-Villaluenga,Cristina TI - Peptides for Health Benefits 2019 : Volume 1 SN - books978-3-03936-081-9 PY - 2020/// CY - Basel, Switzerland PB - MDPI - Multidisciplinary Digital Publishing Institute KW - Research & information: general KW - bicssc KW - Biology, life sciences KW - antihypertensive peptides KW - functional food KW - food-derived KW - fermentation KW - Chlorella sorokiniana KW - in silico KW - BIOPEP-UWM database KW - proteomics KW - bioactive peptides KW - nano liquid chromatography tandem mass spectrometry (nanoLC–nanoESI MS/MS) KW - apolipoprotein E KW - amyloid fibrils KW - Alzheimer’s disease KW - Αβ oligomer KW - amyloid KW - Aβ peptide KW - glioma KW - platelets KW - antiproliferative assay KW - conjugation KW - docetaxel KW - doxorubicin KW - extra domain B KW - fibronectin KW - Fmoc/tBu KW - peptide–drug conjugate KW - prostate cancer KW - solid-phase synthesis KW - targeting KW - acrylamide KW - enteric nervous system KW - galanin KW - pig KW - stomach KW - formyl peptide receptors KW - ligands KW - diseases KW - polymicrobial biofilms KW - intragenic antimicrobial peptide KW - Hs02 KW - Pseudomonas aeruginosa KW - Staphylococcus aureus KW - osteostatin KW - arthritis KW - inflammation KW - immune response KW - cartilage destruction KW - bone erosion KW - collagen KW - hydrolysis KW - enzyme KW - molecular weight KW - sheepskin KW - NF-κB KW - dry-cured pork ham KW - angiotensin I converting enzyme KW - endothelial dysfunction KW - molecular blind docking KW - Lactoferricin B (Lfcin B) KW - Histatin-5 KW - antimicrobial peptides (AMPs) KW - antifungal activity KW - proteome microarray KW - synergy KW - temporin KW - MRSA KW - antimicrobial peptide KW - human keratinocytes KW - pseudin-2 KW - antisepsis, peptide antibiotics KW - neurotensin KW - asthma KW - T cells KW - In situ tetramer staining KW - MHC tetramer KW - antigen-specific KW - confocal microscopy KW - fresh tissue KW - velvet antler KW - alcalase hydrolysate KW - antioxidant peptide KW - protection ability KW - oxidative stress KW - Crassostrea angulata KW - pidotimod KW - CXCR3 KW - monocyte KW - migration KW - PI3K/Akt pathway KW - T cell KW - immunomodulant KW - host defense peptides KW - membrane activity KW - copper KW - piscidins KW - Clostridioides difficile KW - prolactin-releasing peptide KW - GPR10 KW - RF-amide peptides KW - food intake regulation KW - energy expenditure KW - neuroprotection KW - signaling KW - gender differences KW - dyslipidemia KW - obesity KW - hyperglycemia KW - pulmonary emphysema KW - endothelial progenitor cells KW - angiogenic precursor cells KW - pegylated glucagon-like peptide 1 KW - and endothelial regeneration KW - miiuy croaker (Miichthys miiuy) KW - swim bladder KW - FPYLRH KW - antioxidant activity KW - cytoprotective effect KW - antimicrobial peptides KW - antimicrobial resistance KW - AMP identification and design KW - biosynthesis KW - mode of action KW - physico-chemical properties KW - therapeutic potential KW - insects KW - Cecropins KW - Cec-analogs KW - MDR infectious diseases KW - airway inflammation KW - non-atopic asthma KW - hybrid peptide KW - pro-inflammatory cytokines KW - sPLA2 KW - MDA KW - database KW - proteolysis KW - SMILES code KW - foods KW - nutrition KW - chronic diseases KW - nutraceuticals KW - peptide vaccine KW - immune checkpoint inhibitor KW - humanized mouse KW - cancer antigen KW - immune suppression KW - vasoactive intestinal peptide KW - VPAC1 receptor KW - VPAC2 receptor KW - rheumatic diseases KW - inflammatory bowel disease KW - central nervous system diseases KW - type 1 diabetes KW - Sjögren’s syndrome KW - biomarkers KW - human antimicrobial peptides KW - defensins KW - cathelicidins KW - anti-inflammatory KW - pro-inflammatory KW - peptide KW - combinatorial library KW - library design KW - screening KW - mutagenesis KW - prolyl-hydroxyproline (Pro-Hyp) KW - hydroxyprolyl-glycine (Hyp-Gly) KW - collagen peptide KW - fibroblasts KW - fetal bovine serum (FBS) KW - AMD KW - CNV KW - VEGFR1 KW - multimeric peptides KW - oral delivery KW - colorectal cancer KW - cancer stem cells KW - chemoprevention KW - bioactive peptide KW - lunasin KW - ACE-inhibitory activity KW - whey peptides KW - molecular docking KW - hypertension KW - antibiotic resistance KW - cystic fibrosis KW - cryptides KW - anti-biofilm peptides KW - synergistic effects KW - n/a N1 - Open Access N2 - In recent years, peptides have received increased interest from the pharmaceutical industry. The high potency, specificity, and safety profile are the main strengths of bioactive peptides as new and promising therapies that may fill the gap between small molecules and protein drugs. These positive attributes have renewed interest in the discovery, optimization, and development of peptides as pharmacological therapy. Among bioactive peptides, those released from food sources have acquired importance as nutraceutical and active components in functional foods because they possess regulatory functions that can lead to health benefits. This Special Issue covers a selection of recent research papers and reviews in the field of bioactive peptides. It covers all aspects of peptide research in relation to health promotion. In particular, it emphasizes current knowledge and research trends concerning bioactive peptides, including identification and quantification of peptides from new sources, methods for their production and purification, structure–function relationships, mechanisms of action, in vitro and in vivo assays for the evaluation of their bioactivity, physiological evidence to support health benefits, and peptide stability and bioavailability. Papers regarding the development of new drugs, functional foods, or nutraceuticals based on bioactive peptides were also considered UR - https://mdpi.com/books/pdfview/book/2419 UR - https://directory.doabooks.org/handle/20.500.12854/68656 ER -