TY  - GEN
AU  - Adrian,Thomas E
AU  - Sarabia,Francisco
AU  - Cheng-Sanchez,Ivan
TI  - Marine Glycosides
SN  - books978-3-03897-903-6
PY  - 2019///
PB  - MDPI - Multidisciplinary Digital Publishing Institute
KW  - leukemia
KW  - angucycline glycosides
KW  - steroidal glycoside
KW  - antitumor
KW  - deep-sea
KW  - antibacterial
KW  - anticoagulant
KW  - saquayamycin
KW  - marine invertebrate
KW  - triterpene glycoside
KW  - glycosides
KW  - carbohydrate
KW  - polyhydroxysteroidal glycoside
KW  - glycosphingolipids
KW  - triterpene glycosides
KW  - cytotoxic activity
KW  - metabolite profiling
KW  - magnumosides
KW  - antioxidant
KW  - angiogenesis
KW  - Poecillastra compressa
KW  - cucumarioside
KW  - antifungal
KW  - nonholostane
KW  - Eupentacta fraudatrix
KW  - angucycline
KW  - urdamycin
KW  - marine ginseng
KW  - sponge
KW  - antimicrobial
KW  - holostane
KW  - apoptosis
KW  - cholesterol sulfate
KW  - SMMC-7721
KW  - metastases
KW  - Culcita novaeguineae
KW  - natural products
KW  - marine organisms
KW  - liquid chromatography–tandem mass spectrometry
KW  - anti-inflammatory
KW  - tumor growth
KW  - mass spectrometry
KW  - ESI
KW  - total synthesis
KW  - starfish
KW  - sea cucumber
KW  - cytotoxic
KW  - cytotoxicity
KW  - saponins
KW  - Neothyonidium magnum
KW  - glycolipids
KW  - glycoglycerolipids
KW  - Conus pulicarius
KW  - MALDI
KW  - Streptomyces
KW  - glycoside
KW  - radioactive irradiation
KW  - frondoside A
KW  - LC-MS
KW  - invasion
KW  - Holothuroidea
KW  - saponin
KW  - bioactive compounds
KW  - cancer
KW  - structure elucidation
KW  - mangrove-derived Streptomyces
N1  - Open Access
N2  - In recent years, there has been a steady increase in the publication of papers on the chemistry, biology, and potential clinical uses of marine glycosides. Indeed, more than half of the papers published in this field are less than a decade old. Glycosides have been isolated from species as diverse as algae, fungi, anthozoans, and echinoderms. Even fish of the genus Pardachirus produce glycosides, which they use as shark repellents.<false,>The major interest in these compounds as potential drugs stems from their broad spectrum of biological effects. They have been shown to have antimicrobial, antifungal, anti-inflammatory, immune modulatory, and anticancer effects. The anticancer effects of marine glycosides include cell cycle suppression, the induction of apoptosis, and the inhibition of migration, invasion, and metastasis, as well as antiangiogenesis. Marine glycosides influence membrane permeability and have been shown to influence membrane transport at the molecular level through effects on transport carriers and pumps, as well as effects on ligand-gated and voltage-gated channels. Various marine glycosides have been shown to activate sphingomyelinase and ceramide synthesis, to inhibit topoisomerase activity, receptor tyrosine kinase activity, and multidrug resistance protein activity, and to antagonize eicosanoid receptors.<false,>This Special Issue covers the entire scope of marine organism-derived glycosides that are of potential value as pharmaceutical agents or leads. These include, but are not limited to, tetracyclic triterpene glycosides, other triterpene glycosides, steroid glycosides, and glycosides of non-isoprenoid aglycones
UR  - https://mdpi.com/books/pdfview/book/1283
UR  - https://directory.doabooks.org/handle/20.500.12854/52777
ER  -