TY  - GEN
AU  - Di Liegro,Italia
TI  - Genetic and Epigenetic Modulation of Cell Functions by Physical Exercise
SN  - books978-3-03928-481-8
PY  - 2020///
PB  - MDPI - Multidisciplinary Digital Publishing Institute
KW  - TFRC
KW  - single nucleotide polymorphism
KW  - high-density lipoprotein
KW  - blood cell counts
KW  - epigenetics
KW  - intestinal microbiome
KW  - iron metabolism
KW  - Irisin
KW  - exercise and health
KW  - healthy lifestyle
KW  - physical exercise
KW  - single nucleotide polymorphisms
KW  - Taiwan biobank
KW  - obesity
KW  - glucokinase-regulator
KW  - ?-actinin
KW  - body mass index
KW  - hepatic lipase
KW  - Taiwan Biobank
KW  - genotyping
KW  - myokines
KW  - DNA-methylation
KW  - NK
KW  - brain health
KW  - gene expression
KW  - ferritin
KW  - exercise and aging
KW  - exercise
KW  - endurance
KW  - antihypertensive therapy
KW  - genetics
KW  - gut microbiome
KW  - ketogenic diet
KW  - inflammation
KW  - PCBP1
KW  - PCBP2
KW  - marathon runners
KW  - natural killer cell
KW  - behavior
KW  - aerobic exercise
KW  - exercise and neurodegeneration
KW  - BDNF
KW  - gut microbiota
KW  - physical activity
KW  - performance
KW  - lactate
KW  - sport
KW  - ketogenic diet and fat
KW  - body fat
N1  - Open Access
N2  - From an evolutionary perspective, our species has relied upon physical activity for most of its history to survive and has had to escape from predators, to scavenge for food, and to use physique to work or build necessary means for everyday life. Physical activity has been part of our evolution and progress since the very beginning and, consequently, our entire body has been programmed to be active physically. In the last 20 years, scientific research has increasingly shown that our ancient survival principle has beneficial effects not only on the cells and organs involved in physical activities but on the metabolism of the entire organism, influencing the homeostasis and integration of all bodily functions, likely stimulating the production of hormones and other regulatory molecules, with each affecting vital signalling pathways. Most of the web of factors involved in molecular signalling upon exercise are suspected to be centrally controlled by the brain, which has been reported to be deeply modified by physical activity. Such complexity requires a multifaceted approach to shed light on the molecular interactions that occur between physical activity and its outcome at a cellular level
UR  - https://mdpi.com/books/pdfview/book/2259
UR  - https://directory.doabooks.org/handle/20.500.12854/48390
ER  -