TY  - GEN
AU  - Neumann,Dietbert
AU  - Viollet,Benoit
TI  - AMP-Activated Protein Kinase Signalling
SN  - books978-3-03897-663-9
PY  - 2019///
PB  - MDPI - Multidisciplinary Digital Publishing Institute
KW  - n/a
KW  - HDACs
KW  - transcription
KW  - epigenetics
KW  - spermatozoa
KW  - par complex
KW  - A769662
KW  - MDCK
KW  - skeletal muscle
KW  - AID
KW  - phosphorylation
KW  - energy metabolism
KW  - monocytes
KW  - autophagy
KW  - CML
KW  - liver
KW  - hindlimb suspension
KW  - pregnancy
KW  - preeclampsia
KW  - gestational diabetes mellitus
KW  - CaMKK2
KW  - assisted reproduction techniques
KW  - nutrient-sensing signals
KW  - sonic hedgehog
KW  - protein acetylation
KW  - glycogen storage disease
KW  - AMPK
KW  - adenosine monophosphate-activated protein kinase
KW  - AICAR
KW  - indirect calorimetry
KW  - IL-1?
KW  - MyHC I(?)
KW  - HDAC4/5
KW  - endothelial cells
KW  - infection
KW  - hepatocyte
KW  - p70S6K
KW  - lipid metabolism
KW  - host defense
KW  - exercise
KW  - kidney disease
KW  - heat shock protein
KW  - ?RIM
KW  - mycobacteria
KW  - activation loop
KW  - developmental origins of health and disease (DOHaD)
KW  - CREB
KW  - TAK1
KW  - metabolic-inflammation
KW  - phenylephrine
KW  - AMP-activated protein kinase (AMPK)
KW  - KATs
KW  - 2-methoxyestradiol
KW  - DNA methylation
KW  - NLRP3
KW  - pump
KW  - ?-linker
KW  - steatosis
KW  - AMPK kinase
KW  - stress
KW  - endothelial nitric-oxide synthase
KW  - vasodilation
KW  - adherent junctions
KW  - epithelial cells
KW  - glycogen
KW  - Akt
KW  - synaptic activation
KW  - cellular energy sensing
KW  - glucose uptake
KW  - transporter
KW  - co-expression
KW  - atrophy
KW  - nutrigenomics
KW  - motility
KW  - vasoconstriction
KW  - fatty acid oxidation
KW  - oxidative stress
KW  - AS160
KW  - membrane
KW  - histone modification
KW  - sirtuin 1 (SIRT1)
KW  - chromatin remodeling
KW  - insulin signalling
KW  - dietary fatty acids
KW  - ULK
KW  - CMML
KW  - adaptive thermogenesis
KW  - mTOR
KW  - MDS
KW  - mechanical unloading
KW  - AML
KW  - endothelial function
KW  - medulloblastoma
KW  - PKA
KW  - adipose tissue
KW  - NAD<sup>+</sup>
KW  - membranes
KW  - nutrition
KW  - ZO-1
KW  - TBC1D4
KW  - adipocyte
KW  - soluble Adenylyl cyclase
KW  - metabolism
KW  - renin-angiotensin system
KW  - energy utilization
KW  - proteasome
KW  - differentiation
KW  - signaling
KW  - peroxisome proliferator-activated receptor gamma coactivator 1-? (PGC1?)
KW  - hypertrophy
KW  - AMP-activated protein kinase
KW  - metabolic disease
KW  - LKB1
KW  - soleus muscle
KW  - macrophages
KW  - Immediate early genes
KW  - CBS
KW  - beiging
KW  - motor endplate remodeling
KW  - ionomycin
KW  - nectin-afadin
KW  - tight junctions
KW  - resveratrol
KW  - protein kinase B
KW  - regrowth
KW  - mitochondria
KW  - protein synthesis
KW  - energy deficiency
KW  - catechol-<i>O</i>-methyltransferase
KW  - fiber-type
KW  - microarrays
KW  - carrier
KW  - acetyl-CoA
KW  - hypertension
KW  - 3T3-L1
KW  - hypothalamus
KW  - food intake
N1  - Open Access
N2  - Starting from a kinase of interest, AMP-activated protein kinase (AMPK) has gone far beyond an average biomolecule. Being expressed in all mammalian cell types and probably having a counterpart in every eukaryotic cell, AMPK has attracted interest in virtually all areas of biological research. Structural and biophysical insights have greatly contributed to a molecular understanding of this kinase. From good old protein biochemistry to modern approaches, such as systems biology and advanced microscopy, all disciplines have provided important information. Thus, multiple links to cellular events and subcellular localizations have been established. Moreover, the crucial involvement of AMPK in human health and disease has been evidenced. AMPK accordingly has moved from an interesting enzyme to a pharmacological target. However, despite our extensive current knowledge about AMPK, the growing community is busier than ever. This book provides a snapshot of recent and current AMPK research with an emphasis on work providing molecular insight, including but not limited to novel physiological and pathological functions, or regulatory mechanisms. Up-to-date reviews and research articles are included
UR  - https://mdpi.com/books/pdfview/book/1169
UR  - https://directory.doabooks.org/handle/20.500.12854/40775
ER  -