Lozach, Pierre-Yves

Cell Biology of Viral Infections - Basel, Switzerland MDPI - Multidisciplinary Digital Publishing Institute 2021 - 1 electronic resource (418 p.)

Open Access

Viruses exhibit an elegant simplicity as they are so basic, but so frightening. Although only a few are life threatening, they have substantial implications for human health and the economy, as exemplified by the ongoing coronavirus pandemic. Viruses are rather small infectious agents found in all types of life forms, from animals and plants to prokaryotes and archaebacteria. They are obligate intracellular parasites, and as such, subvert many molecular and cellular processes of the host cell to ensure their own replication, amplification, and subsequent spread. This Special Issue addresses the cell biology of viral infections based on a collection of original research articles, communications, opinions, and reviews on various aspects of virus–host cell interactions. Together, these articles not only provide a glance into the latest research on the cell biology of viral infections but also include novel technological developments.


Creative Commons


English

books978-3-0365-0147-5 9783036501468 9783036501475

10.3390/books978-3-0365-0147-5 doi


Research & information: general
Biology, life sciences

ectoderm mesoderm human development embryogenesis interferon response interferon-induced genes self-organizing map (SOM) data portrayal epigenetic signature embryoid body TGF-β and Wnt/β-catenin pathway interferon tumor necrosis factor STAT interferon regulatory factor antiviral autoimmunity inflammation hepatitis C virus HCV erlin-1 erlin-2 host factor endoplasmic reticulum RNA replication protein production virus production lipid droplet TAP-GFP fluorescent TAP platform antigen presentation MHC I immune evasion BoHV-1 UL49.5 virus calcium channels calcium pumps virus–host interaction Ebola virus filovirus inclusion bodies NXF1 liquid organelles mRNA export cancer immunotherapy oncolytic virus herpes simplex virus immune checkpoint inhibitor angiogenesis inhibitor rabies uDISCO 3D imaging rabies pathogenicity astrocyte infection metabolism apoptosis autophagy HIV-1 spread cell-free infection cell–cell transmission 3D cultures mathematical modeling environmental restriction CAD pyrimidine synthesis HEV particle production viral replication virus entry hantavirus Tula virus replication factory RNA synthesis Golgi stress granules actin cytoskeleton nucleocapsid transport Arp2/3 complex ERAP2 ERAP2/Iso3 microbial infections alternative splicing SARS-CoV-2 host cell response coronavirus MERS-CoV SARS-CoV sialic acid Siglec antiviral peptide enveloped viruses membrane phosphatidylserine envelope disruption membrane damage antiviral autophagy galectin bacterial invasion adenovirus lysophagy ESCRT machinery cedar virus henipavirus fusion protein endocytosis biological activity feline coronavirus feline enteric coronavirus FECV feline infectious peritonitis virus FIPV feline intestinal organoids alphaviruses cell death mosquito tolerance