TY - GEN AU - Gámiz-Gracia,Laura AU - García-Campaña,Ana M. AU - Arroyo-Manzanares,Natalia AU - Gámiz-Gracia,Laura AU - García-Campaña,Ana M. AU - Arroyo-Manzanares,Natalia TI - Application of LC-MS/MS in the Mycotoxins Studies SN - books978-3-03936-207-3 PY - 2020/// CY - Basel, Switzerland PB - MDPI - Multidisciplinary Digital Publishing Institute KW - Medicine KW - bicssc KW - cereals KW - mycotoxigenic fungi KW - phylogeny KW - deoxynivalenol KW - zearalenone KW - Sub-Saharan Africa KW - aflatoxins KW - mycotoxins KW - total diet study KW - food contaminants KW - LC-MS/MS KW - Alternaria toxins KW - grape KW - modified QuEChERS KW - UHPLC-MS/MS KW - n/a KW - traditional sorghum malts KW - Aspergillus KW - LC/MS/MS KW - Biomarkers KW - exposure KW - LC-HRMS KW - pig KW - broiler chicken KW - multi-mycotoxin KW - stability KW - malting KW - brewing KW - beer KW - feed KW - liquid chromatography KW - fluorescence detection KW - mass spectrometry KW - solid-liquid extraction KW - co-occurrence KW - metabolism KW - high-resolution mass spectrometry (HRMS) KW - microsomal incubation KW - glucuronidation KW - human KW - biomonitoring KW - UPLC-MS/MS KW - rumen fluid KW - maize silage KW - matrix-matched KW - moniliformin KW - lanthanide complexes KW - LC-UV KW - collaborative study KW - isotopic dilution KW - compliance KW - infant food KW - emergent mycotoxins KW - urine KW - dispersive solid-phase extraction KW - magnetic carbon nanotube composite KW - pesticides KW - Q-Exactive Orbitrap KW - CBD capsule KW - nutraceutical KW - Fusarium KW - maize KW - masked mycotoxins KW - agricultural regions KW - South Africa KW - Mycotoxins KW - exposure assessment KW - Algeria KW - mixed feed rations KW - QuEChERS KW - dispersive solid phase extraction KW - high-resolution mass spectrometry KW - data independent SWATH N1 - Open Access N2 - Mycotoxins are secondary metabolites produced by the fungi of different species (mainly Aspergillus, Fusarium, and Penicillium), with toxic effects for humans and animals. These mycotoxins can contaminate food and feed. The European Union (EU) has established the maximum permitted or recommended levels for well-known mycotoxins in different foodstuffs. However, there are other mycotoxins that are not included in the regulations: the “emerging mycotoxins” (whose toxicity is still not clear), and the “modified or masked mycotoxins” (produced as a consequence of a detoxification strategy of the host plant of the fungus or during food processing). These mycotoxins could pose a risk and should also be taken into account. In order to assure consumers’ health, analytical methods for the accurate determination of mycotoxins in different food matrices and feeds are required. In this sense, liquid chromatography tandem mass spectrometry (LC–MS/MS) is a powerful tool for their unique identification and quantification. Moreover, the use of high-resolution mass spectrometry (HRMS) allows one to identify novel mycotoxins and targeted/untargeted approaches for study. This Special Issue compiles recent applications of LC–MS/MS in mycotoxin studies, as well as the development and validation of new analytical methods for their identification and quantification in different food matrices and feed, occurrence studies, and the biomonitoring of mycotoxins and their metabolites in biological fluids UR - https://mdpi.com/books/pdfview/book/2382 UR - https://directory.doabooks.org/handle/20.500.12854/68620 ER -