Baer, Patrick C. <br/><br/>
Kidney Inflammation, Injury and Regeneration 2020 

 - Basel, Switzerland  MDPI - Multidisciplinary Digital Publishing Institute  2021 
 - 1 electronic resource (318 p.) 
<br/><br/> Open Access 
<br/><br/> Acute kidney injury (AKI) is still associated with high morbidity and mortality incidence rates, and also bears an elevated risk of chronic kidney disease in the sequel. Whereas the kidney has a remarkable capacity for regeneration after injury and may recover completely depending on the type of renal lesions, the options for clinical intervention are restricted to fluid management and extracorporeal kidney support. The development of novel therapies to prevent AKI, to improve renal regeneration capacity after AKI, and to preserve renal function—in both the short- and long-term—is urgently needed. This Special Issue includes papers investigating the pathological mechanisms of renal inflammation and AKI and diagnostics using new biomarkers. Furthermore, experimental in vitro and in vivo studies examining potential new approaches to attenuate kidney dysfunction are included, as well as review articles. 
<br/><br/><br/>Creative Commons 
<br/><br/><br/>English 
<br/><br/><label>ISBN: </label>books978-3-0365-2369-9 9783036523705 9783036523699 
<br/><br/><label>Standard No.: </label>10.3390/books978-3-0365-2369-9  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Medicine
<br/><br/><label>Subjects--Index Terms: </label>inflammation chronic kidney disease anemia anemia of inflammation ESA hyporesponsiveness renal tubular epithelial cells macrophages lipocalin-2 iron cilastatin hypoxia inducible factor-1-α ischemia-reperfusion injury acute kidney injury cyclophilin A fibrosis renal fibrosis tubular necrosis preeclampsia podocytes VEGF FSGS proteinuria endocan ESM-1 renal replacement therapy kidney transplantation biomarker diabetic nephropathy focal segmental glomerulosclerosis innate immunity membranous nephropathy minimal change diseases TLR NOX1 ML171 reactive oxygen species ERK T cells glomerulonephritis chemokines renal disease DJ-1 ND-13 renal inflammation oxidative stress UUO autophagy apoptosis trehalose simvastatin endotoxin tubular apoptosis cytochrome C Bcl-XL survivin hypercholesterolemia xanthine oxidase NF-κB pathway tertiary lymphoid organs B cells BAFF kidney fibrosis myofibroblast activation extracellular matrix Hippo pathway verteporfin IgAN CKD progression ACEI corticosteroids costimulation coinhibition kidney transplant SPR protein binding affinity adaptive immunity epithelial-to-mesenchymal transition E. cava extracts dieckol spontaneously hypertensive rats angiotensin II n/a