Yoon, Jong <br/><br/>
Multi-Omics for the Understanding of Brain Diseases 

 - Basel, Switzerland  MDPI - Multidisciplinary Digital Publishing Institute  2021 
 - 1 electronic resource (204 p.) 
<br/><br/> Open Access 
<br/><br/> Omics technologies such as proteomics, genomics, and metabolomics are widely applied for the identification and characterization of new molecular signatures. However, molecular profiling that makes it possible to understand neurodegenerative diseases has been relatively insufficient. Brain diseases such as neurodegenerative diseases and emotional disorders need integrative understanding which draws on a more reliable hypothesis for pathology, which can be accomplished via in-depth study of molecular information. Recently, multi-omics technologies have been eagerly applied to a diverse range of diseases. As this includes multiple molecular profiling, metadata, and Big Data processing with informatics and computer science, it is possible to provide new macroscopic and microscopic insights in order to better understand diseases. This Special Issue will introduce recent technological advances in multi-omics and the application of omics technology to brain diseases. 
<br/><br/><br/>Creative Commons 
<br/><br/><br/>English 
<br/><br/><label>ISBN: </label>books978-3-0365-2603-4 9783036526027 9783036526034 
<br/><br/><label>Standard No.: </label>10.3390/books978-3-0365-2603-4  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Research & information: general
<br/><br/><label>Subjects--Index Terms: </label>schizophrenia abnormal behavior gene set region differentially expressed genes de novo mutation copy number variant SIDS newborn infant genetic polymorphism neurotransmitter epigenetics epigenome zinc finger domain zinc finger motif zinc finger proteins zinc metalloproteins flow infusion analysis chloride adducts ceramides sphingolipids glycerophosphocholines human brain NAD+ nicotinamide ageing plasma biomarker CNV PPI spatiotemporal network chromosome 22q11.21 DGCR8 Orthosiphon stamineus plant-derived proteins neuroprotective SH-SY5Y cell model hydrogen peroxide CSF miRNAs neurological diseases OpenArray morphine withdrawal brain proteomics synaptic plasticity Alzheimer’s disease microfluidics lab-on-chip 3D culture organ-on-chip n/a