TY - GEN AU - Yoon,Jong AU - Villa,Chiara AU - Yoon,Jong AU - Villa,Chiara TI - Multi-Omics for the Understanding of Brain Diseases SN - books978-3-0365-2603-4 PY - 2021/// CY - Basel, Switzerland PB - MDPI - Multidisciplinary Digital Publishing Institute KW - Research & information: general KW - bicssc KW - schizophrenia KW - abnormal behavior gene set KW - region KW - differentially expressed genes KW - de novo mutation KW - copy number variant KW - SIDS KW - newborn infant KW - genetic polymorphism KW - neurotransmitter KW - epigenetics KW - epigenome KW - zinc finger domain KW - zinc finger motif KW - zinc finger proteins KW - zinc metalloproteins KW - flow infusion analysis KW - chloride adducts KW - ceramides KW - sphingolipids KW - glycerophosphocholines KW - human brain KW - NAD+ KW - nicotinamide KW - ageing KW - plasma KW - biomarker KW - CNV KW - PPI KW - spatiotemporal network KW - chromosome 22q11.21 KW - DGCR8 KW - Orthosiphon stamineus KW - plant-derived proteins KW - neuroprotective KW - SH-SY5Y cell model KW - hydrogen peroxide KW - CSF KW - miRNAs KW - neurological diseases KW - OpenArray KW - morphine KW - withdrawal KW - brain KW - proteomics KW - synaptic plasticity KW - Alzheimer’s disease KW - microfluidics KW - lab-on-chip KW - 3D culture KW - organ-on-chip KW - n/a N1 - Open Access N2 - Omics technologies such as proteomics, genomics, and metabolomics are widely applied for the identification and characterization of new molecular signatures. However, molecular profiling that makes it possible to understand neurodegenerative diseases has been relatively insufficient. Brain diseases such as neurodegenerative diseases and emotional disorders need integrative understanding which draws on a more reliable hypothesis for pathology, which can be accomplished via in-depth study of molecular information. Recently, multi-omics technologies have been eagerly applied to a diverse range of diseases. As this includes multiple molecular profiling, metadata, and Big Data processing with informatics and computer science, it is possible to provide new macroscopic and microscopic insights in order to better understand diseases. This Special Issue will introduce recent technological advances in multi-omics and the application of omics technology to brain diseases UR - https://mdpi.com/books/pdfview/book/4694 UR - https://directory.doabooks.org/handle/20.500.12854/77075 ER -