TY - GEN AU - Ciccodicola,Alfredo AU - Casamassimi,Amelia TI - Transcriptional Regulation: Molecules, Involved Mechanisms and Misregulation SN - books978-3-03921-266-8 PY - 2019/// PB - MDPI - Multidisciplinary Digital Publishing Institute KW - transcription factor KW - n/a KW - transcription KW - self-incompatibility KW - cytogenetics KW - epigenetics KW - selenocysteine KW - tea KW - AP-2? KW - nonsense-mediated decay KW - transcriptomics KW - Akt1 KW - promoter KW - cell metabolism KW - pediveliger larvae KW - Patau Syndrome KW - tristetraprolin (TTP) KW - long non-coding RNA (lncRNA) KW - pregnancy KW - G-quadruplex KW - glioblastoma KW - placenta KW - PRDM gene family KW - circRNA-disease associations KW - bioadhesive KW - gene expression KW - Crassostrea gigas KW - transcription regulation KW - cell differentiation KW - RNA interference KW - transcriptome KW - inflammatory response KW - FOXO1 KW - Adiponectin KW - liquid chromatograph-tandem mass spectrometer (LC-MS/MS) KW - selenium KW - selenocysteine insertion sequence KW - inflammation KW - selenoproteins KW - research methods KW - nutritional status KW - structures and functions KW - CRISPR/Cas9 KW - fertilization KW - melanin KW - differentially expressed genes KW - tyrosinase KW - posttranscriptional regulation KW - major depressive disorder KW - human malignancies KW - pathway KW - CDKN1C KW - transcription factors KW - p57Kip2 KW - enhancer activity KW - mouse KW - disorders KW - high-throughput RNA sequencing (RNA-Seq) KW - TCGA data analysis KW - RNA-seq KW - heterogeneous network KW - insect KW - and drug design KW - therapeutic targets KW - mechanisms KW - obesity KW - Pacific oyster KW - Rsh regulon KW - common pathway KW - Pax3 KW - somatic mutations KW - nutrition KW - molecular docking KW - bioinformatics KW - interactome KW - long non-coding RNAs KW - transcriptional regulation KW - Pteria penguin (Röding KW - Adiponectin receptors KW - transcriptome profiling KW - 1798) KW - N-acyl-l-homoserine lactone KW - ppGpp KW - tumorigenesis KW - sphingomonads KW - human KW - disease KW - adenosine and uridine-rich elements (AREs) KW - progress and prospects KW - miR-25-3p KW - acute leukemia KW - Novosphingobium pentaromativorans US6-1 KW - microscopy KW - cancer KW - molecular pathways KW - causal inference N1 - Open Access N2 - Transcriptional regulation is a critical biological process involved in the response of a cell, a tissue or an organism to a variety of intra- and extra-cellular signals. Besides, it controls the establishment and maintenance of cell identity throughout developmental and differentiation programs. This highly complex and dynamic process is orchestrated by a huge number of molecules and protein networks and occurs through multiple temporal and functional steps. Of note, many human disorders are characterized by misregulation of global transcription since most of the signaling pathways ultimately target components of transcription machinery. This book includes a selection of papers that illustrate recent advances in our understanding of transcriptional regulation and focuses on many important topics, from cis-regulatory elements to transcription factors, chromatin regulators and non-coding RNAs, other than several transcriptome studies and computational analyses UR - https://mdpi.com/books/pdfview/book/1459 UR - https://directory.doabooks.org/handle/20.500.12854/61178 ER -