TY  - GEN
AU  - Burz,David S.
AU  - Shekhtman,Alexander
TI  - In-Cell NMR Spectroscopy: Biomolecular Structure and Function
SN  - books978-3-03928-255-5
PY  - 2020///
PB  - MDPI - Multidisciplinary Digital Publishing Institute
KW  - protein NMR
KW  - time-resolved NMR
KW  - Ribosome
KW  - structural calculation 4
KW  - crystalline and amorphous starch
KW  - in-cell NMR
KW  - protein dynamics
KW  - DNP
KW  - protein modification
KW  - Tau
KW  - spectrum reconstruction 3
KW  - mRNA
KW  - Thioredoxin
KW  - protein structure
KW  - protein interactions
KW  - drug discovery
KW  - protein structure determination 1
KW  - review
KW  - enzyme activity
KW  - MARK2 phosphorylation
KW  - post-translational modifications
KW  - Dihydrofolate reductase
KW  - mammalian cells
KW  - target engagement
KW  - non-uniform sampling 2
KW  - paramagnetic effects
KW  - protein structure-function
KW  - cross-correlated relaxation
KW  - structure function
KW  - rRNA
KW  - 2D INADEQUATE
KW  - lipid membrane
KW  - Thymidylate synthase
KW  - whole cell NMR
KW  - enzyme kinetics
KW  - magic-angle spinning
KW  - live cell
KW  - solid-state NMR
KW  - Adenylate kinase
KW  - DNA
KW  - in-situ NMR
KW  - antimicrobial peptide
KW  - NMR spectroscopy
KW  - intrinsically disordered proteins
N1  - Open Access
N2  - This Special Issue examines state-of-the-art in-cell NMR spectroscopy as it relates to biological systems of increasing complexity. The compendia of research and recent innovations from prominent laboratories in the field of solid state and solution in-cell NMR spectroscopy, metabolomics and technology development are presented. The work establishes in-cell NMR spectroscopy as the premier method for determining the structures and interaction capabilities of biological molecules at high resolution within the delicately intricate interior of living cells, and the means of utilizing cells as living laboratories to directly assess the effects of exogenous and endogenous stimuli on cell physiology.]
UR  - https://mdpi.com/books/pdfview/book/2256
UR  - https://directory.doabooks.org/handle/20.500.12854/50093
ER  -