TY  - GEN
AU  - Roberts,Angela
TI  - The Multi-Dimensional Contributions of Prefrontal Circuits to Emotion Regulation during Adulthood and Critical Stages of Development
SN  - books978-3-03921-703-8
PY  - 2019///
PB  - MDPI - Multidisciplinary Digital Publishing Institute
KW  - norepinephrine
KW  - medial prefrontal cortex
KW  - fear extinction
KW  - emotion regulation
KW  - emotion processing
KW  - connectivity
KW  - anticipatory arousal
KW  - Pavlovian
KW  - triadic neural systems model
KW  - prelimbic
KW  - development
KW  - positive and negative
KW  - rat
KW  - Williams Syndrome
KW  - psychological treatment
KW  - glia density
KW  - anxiety
KW  - fMRI
KW  - area 25
KW  - anhedonia
KW  - adolescence
KW  - adolescent
KW  - autonomic
KW  - amygdala
KW  - neuron density
KW  - neural
KW  - prefrontal cortex
KW  - reliability
KW  - functional magnetic resonance imaging (fMRI)
KW  - networks
KW  - cAMP
KW  - cognitive control
KW  - extinction
KW  - infralimbic
KW  - NMDA
KW  - reward
KW  - calcium
KW  - stress adolescence
KW  - BDNF
KW  - machine learning
KW  - negative affect
KW  - hierarchical control
KW  - emotion
KW  - occasion setting
KW  - serotonin transporter
KW  - ventromedial prefrontal cortex
KW  - psychophysiology
KW  - depression
KW  - aging
KW  - dopamine
KW  - age
N1  - Open Access
N2  - The prefrontal cortex (PFC) plays a pivotal role in regulating our emotions. The importance of ventromedial regions in emotion regulation, including the ventral sector of the medial PFC, the medial sector of the orbital cortex and subgenual cingulate cortex, have been recognized for a long time. However, it is increasingly apparent that lateral and dorsal regions of the PFC, as well as neighbouring dorsal anterior cingulate cortex, also play a role. Defining the underlying psychological mechanisms by which these functionally distinct regions modulate emotions and the nature and extent of their interactions is a critical step towards better stratification of the symptoms of mood and anxiety disorders. It is also important to extend our understanding of these prefrontal circuits in development. Specifically, it is important to determine whether they exhibit differential sensitivity to perturbations by known risk factors such as stress and inflammation at distinct developmental epochs. This Special Issue brings together the most recent research in humans and other animals that addresses these important issues, and in doing so, highlights the value of the translational approach
UR  - https://mdpi.com/books/pdfview/book/1846
UR  - https://directory.doabooks.org/handle/20.500.12854/54046
ER  -