Geometric Regularization in Bioluminescence Tomography

By: Material type: ArticleArticleLanguage: English Publication details: KIT Scientific Publishing 2014Description: 1 electronic resource (IX, 185 p. p.)ISBN:
  • KSP/1000037411
  • 9783731501428
Subject(s): Online resources: Summary: Bioluminescence tomography is a recent biomedical imaging technique which allows to study molecular and cellular activities in vivo. From a mathematical point of view, it is an ill-posed inverse source problem: the location and the intensity of a photon source inside an organism have to be determined, given the photon count on the organism's surface. To face the ill-posedness of this problem, a geometric regularization approach is introduced, analyzed and numerically verified in this book.
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Bioluminescence tomography is a recent biomedical imaging technique which allows to study molecular and cellular activities in vivo. From a mathematical point of view, it is an ill-posed inverse source problem: the location and the intensity of a photon source inside an organism have to be determined, given the photon count on the organism's surface. To face the ill-posedness of this problem, a geometric regularization approach is introduced, analyzed and numerically verified in this book.

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