Oxidative Stress in Diabetic Retinopathy
Material type:
ArticleLanguage: English Publication details: Basel, Switzerland MDPI - Multidisciplinary Digital Publishing Institute 2021Description: 1 electronic resource (322 p.)ISBN: - books978-3-0365-0449-0
- 9783036504483
- 9783036504490
- Medicine
- eicosanoids
- oxidative stress
- diabetic retinopathy
- cyclooxygenase
- lipoxygenase
- Cytochrome P450
- HDAC6
- tubastatin A
- retinal endothelial cells
- retinal endothelial cell senescence
- db/db mice
- Cinnamomi Ramulus
- Paeoniae Radix
- CPA4-1
- blood-retinal barrier
- occludin
- human retina
- epiretinal membrane
- internal limiting membrane
- vitreoretinal surgery
- macular hole
- proliferative diabetic retinopathy
- antioxidants
- diabetes mellitus
- free radicals
- high-mobility group box 1 (HMGB1)
- inflammatory pathways
- novel therapies
- diabetic retinopathy (DR)
- inflammation
- angiogenesis
- extracellular vesicles
- miRNA
- biomarkers
- apoptosis
- fenofibrate
- thioredoxin
- hyperglycemia
- astaxanthin
- carotenoid
- reactive oxygen species
- photoreceptor cells
- PI3K
- Nrf2
- eicosapentaenoic acid (EPA)
- docosahexaenoic acid (DHA)
- retinal pigment epithelium
- antioxidant
- ascorbic acid
- retinal disease
- vitamin D
- GLP-1
- superoxide dismutase
- biomarkers of diabetic retinopathy
- metabolic memory
- tear film
- aqueous humor
- vitreous humor
- mitochondria
- redox
- photoreceptor
- glycation
- aging
- glyoxalase
- n/a
Open Access star Unrestricted online access
The combination of an increasing prevalence of diabetes and the aging of populations enables the appearance of a greater number of associated complications such as diabetic retinopathy. Diabetic retinopathy is the leading cause of preventable vision loss in working-age adults. The objective of this Special Issue is to highlight the existing evidence regarding the relationship between oxidative stress and low-grade chronic inflammation induced by hyperglycemia with the development and progression of diabetic retinopathy, with an emphasis on the importance of early diagnosis and the use of antioxidant and anti-inflammatory approaches to prevent or delay the harmful effects of diabetes on retinal tissue.
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