| 000 | 02902naaaa2200277uu 4500 | ||
|---|---|---|---|
| 001 | https://directory.doabooks.org/handle/20.500.12854/70301 | ||
| 020 | _aintechopen.80593 | ||
| 024 | 7 |
_a10.5772/intechopen.80593 _cdoi |
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| 041 | 0 | _aEnglish | |
| 042 | _adc | ||
| 072 | 7 |
_aMJCM _2bicssc |
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| 100 | 1 |
_aMaksimović, Zoran _4auth |
|
| 700 | 1 |
_aSamardžić, Stevan _4auth |
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| 245 | 1 | 0 | _aChapter Herbal Medicinal Products in the Treatment of Osteoarthritis |
| 260 |
_bInTechOpen _c2019 |
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| 506 | 0 |
_aOpen Access _2star _fUnrestricted online access |
|
| 520 | _aOsteoarthritis (OA) is the most common form of arthritis, which represents a substantial economic burden for society and significantly affects patients’ quality of life. Current conventional treatments of OA may be insufficiently effective and unsafe. In an attempt to overcome these limitations, many patients use herbal medicinal products (HMPs) and dietary supplements. A considerable number of herbal drugs and preparations (e.g., willow bark, Salicis cortex; devil’s claw root, Harpagophyti radix; blackcurrant leaf, Ribis nigri folium; nettle leaf/herb, Urticae folium/herba; meadowsweet/meadowsweet flower, Filipendulae ulmariae herba/flos; rosemary leaf/oil, Rosmarini folium/aetheroleum; and juniper oil, Juniperi aetheroleum) are traditionally employed to relieve minor articular pain. Active constituents (e.g., sesquiterpene lactones, triterpenic acids, diarylheptanoids, iridoid glycosides, phenolic glycosides, procyanidins, and alkaloids) are not often fully known. Experimental studies suggest that herbal extracts/compounds are able to suppress inflammation, inhibit catabolic processes, and stimulate anabolic processes relevant to OA. Therapeutic benefit of most HMPs is expected solely from the experience of their long-standing traditional use. Efficacy and safety of several HMPs were assessed in clinical trials. The growing body of preclinical and clinical evidence provides rationale for the use of herbal products in the treatment of OA. However, at present, they cannot be recommended to patients with confidence. | ||
| 540 |
_aCreative Commons _fhttps://creativecommons.org/licenses/by/3.0/ _2cc _4https://creativecommons.org/licenses/by/3.0/ |
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| 546 | _aEnglish | ||
| 650 | 7 |
_aImmunology _2bicssc |
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| 653 | _aosteoarthritis, herbal medicinal products, medicinal plants, mechanism of action, active constituents, clinical efficacy | ||
| 773 | 1 | 0 |
_0OAPEN Library ID: ONIX_20210602_10.5772/intechopen.80593_432 _7nnaa |
| 856 | 4 | 0 |
_awww.oapen.org _uhttps://library.oapen.org/bitstream/20.500.12657/49318/1/63298.pdf _70 _zDOAB: download the publication |
| 856 | 4 | 0 |
_awww.oapen.org _uhttps://library.oapen.org/bitstream/20.500.12657/49318/1/63298.pdf _70 _zDOAB: download the publication |
| 856 | 4 | 0 |
_awww.oapen.org _uhttps://directory.doabooks.org/handle/20.500.12854/70301 _70 _zDOAB: description of the publication |
| 999 |
_c38251 _d38251 |
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