000 02963naaaa2200313uu 4500
001 https://directory.doabooks.org/handle/20.500.12854/70158
020 _aintechopen.72532
024 7 _a10.5772/intechopen.72532
_cdoi
041 0 _aEnglish
042 _adc
072 7 _aPSAN
_2bicssc
100 1 _aSchubert, Nicole
_4auth
700 1 _aAxer, Markus
_4auth
700 1 _aPietrzyk, Uwe
_4auth
700 1 _aAmunts, Katrin
_4auth
245 1 0 _aChapter 3D Polarized Light Imaging Portrayed: Visualization of Fiber Architecture Derived from 3D-PLI
260 _bInTechOpen
_c2018
506 0 _aOpen Access
_2star
_fUnrestricted online access
520 _a3D polarized light imaging (3D-PLI) is a neuroimaging technique that has recently opened up new avenues to study the complex architecture of nerve fibers in postmortem brains at microscopic scales. In a specific voxel-based analysis, each voxel is assigned a single 3D fiber orientation vector. This leads to comprehensive 3D vector fields. In order to inspect and analyze such high-resolution fiber orientation vector field, also in combination with complementary microscopy measurements, appropriate visualization techniques are essential to overcome several challenges, such as the massive data sizes, the large amount of both unique and redundant information at different scales, or the occlusion issues of inner structures by outer layers. Here, we introduce a comprehensive software tool that is able to visualize all information of a typical 3D-PLI dataset in an adequate and sophisticated manner. This includes the visualization of (i) anatomic structural and fiber architectonic data in one representation, (ii) a large-scale fiber orientation vector field, and (iii) a clustered version of the field. Alignment of a 3D-PLI dataset to an appropriate brain atlas provides expert-based delineation, segmentation, and, ultimately, visualization of selected anatomical structures. By means of these techniques, a detailed analysis of the complex fiber architecture in 3D is feasible.
540 _aCreative Commons
_fhttps://creativecommons.org/licenses/by/3.0/
_2cc
_4https://creativecommons.org/licenses/by/3.0/
546 _aEnglish
650 7 _aNeurosciences
_2bicssc
653 _apolarized light imaging, scientific visualization, neuroinformatics, neuroimaging and fiber architecture
773 1 0 _0OAPEN Library ID: ONIX_20210602_10.5772/intechopen.72532_378
_7nnaa
856 4 0 _awww.oapen.org
_uhttps://library.oapen.org/bitstream/20.500.12657/49264/1/58247.pdf
_70
_zDOAB: download the publication
856 4 0 _awww.oapen.org
_uhttps://library.oapen.org/bitstream/20.500.12657/49264/1/58247.pdf
_70
_zDOAB: download the publication
856 4 0 _awww.oapen.org
_uhttps://library.oapen.org/bitstream/20.500.12657/49264/1/58247.pdf
_70
_zDOAB: download the publication
856 4 0 _awww.oapen.org
_uhttps://directory.doabooks.org/handle/20.500.12854/70158
_70
_zDOAB: description of the publication
999 _c42829
_d42829