000 04422naaaa2201057uu 4500
001 https://directory.doabooks.org/handle/20.500.12854/69113
005 20220219222646.0
020 _abooks978-3-03943-167-0
020 _a9783039431663
020 _a9783039431670
024 7 _a10.3390/books978-3-03943-167-0
_cdoi
041 0 _aEnglish
042 _adc
072 7 _aGP
_2bicssc
072 7 _aPS
_2bicssc
100 1 _aKasper, Michael
_4edt
700 1 _aMühlfeld, Christian
_4edt
700 1 _aKasper, Michael
_4oth
700 1 _aMühlfeld, Christian
_4oth
245 1 0 _aThe Alveolar Epithelium : Mechanisms of Injury and Repair
260 _aBasel, Switzerland
_bMDPI - Multidisciplinary Digital Publishing Institute
_c2020
300 _a1 electronic resource (222 p.)
506 0 _aOpen Access
_2star
_fUnrestricted online access
520 _aAlveolar epithelial cells (AECs) of the lung are important contributors to pulmonary immune functions and to pulmonary development and alveolar repair mechanisms following lung injury. AECI, together with the capillary endothelium, form the extremely thin barrier between alveolar air and blood. AECII produce and metabolize the surface-tension lowering and immune-modulating surfactant and are the progentiors of AECI. A great variety of processes rely on their normal functioning, including maintenance of the alveolar barrier; innate immune defense; and processes of differentiation, senescence, apoptosis, and autophagy. The wide range of AEC functions is nicely reflected by the diversity of topics addressed by the four review and eight original articles contained in this Special Issue of the International Journal of Molecular Sciences. Beyond the broad spectrum of topics, the authors of this issue also made use of an impressive variety of analytical methods, thus further illustrating the fascinating diversity of aspects related to AEC biology.
540 _aCreative Commons
_fhttps://creativecommons.org/licenses/by/4.0/
_2cc
_4https://creativecommons.org/licenses/by/4.0/
546 _aEnglish
650 7 _aResearch & information: general
_2bicssc
650 7 _aBiology, life sciences
_2bicssc
653 _aJAM-A
653 _aP2X7 receptor
653 _amouse lung
653 _aalveolar epithelium
653 _ableomycin-induced lung injury
653 _aGSK-3β
653 _adietary sugar
653 _ahyperglycemia
653 _alung mechanics
653 _aalveolar septal composition
653 _aphysical activity
653 _aextracellular matrix remodeling
653 _ahigh-altitude pulmonary edema
653 _aacute mountain sickness
653 _aoxygen diffusion limitation
653 _asurfactant protein B
653 _aatelectrauma
653 _aalveolar fluid
653 _aacinar micromechanics
653 _aacute lung injury
653 _aautophagy
653 _alysosome
653 _alysosomal membrane permeability
653 _amitochondria
653 _apneumocyte
653 _amicroRNA-21
653 _aalveolar micromechanics
653 _astructural remodeling
653 _ainflammatory signaling
653 _alung
653 _aalveolus
653 _atype 1 alveolar epithelial cell
653 _atype 2 alveolar epithelial cell
653 _afocused ion beam scanning electron microscopy
653 _a3D reconstruction
653 _acarbon dioxide
653 _ahypercapnia
653 _aNa,K-ATPase
653 _aendoplasmic reticulum
653 _asodium transport
653 _aprotein oxidation
653 _aalveolar epithelial cells
653 _apulmonary fibrosis
653 _aepithelial cell dysfunction
653 _astem cell exhaustion
653 _apneumonia
653 _anecrotizing
653 _aregeneration
653 _amodel
653 _abovine
653 _achlamydia
653 _aalveoli
653 _aair-blood barrier
653 _aepithelium
653 _aair-liquid interface
653 _aalveolar lining layer
653 _aglycocalyx
653 _asurfactant
653 _alung injury
653 _alung regeneration
856 4 0 _awww.oapen.org
_uhttps://mdpi.com/books/pdfview/book/2885
_70
_zDOAB: download the publication
856 4 0 _awww.oapen.org
_uhttps://directory.doabooks.org/handle/20.500.12854/69113
_70
_zDOAB: description of the publication
999 _c47928
_d47928