000			02157naaaa2200337uu 4500
001			https://directory.doabooks.org/handle/20.500.12854/52944
005			20220219223234.0
020			_a978-2-88919-929-7
020			_a9782889199297
024	7		_a10.3389/978-2-88919-929-7 _cdoi
041	0		_aEnglish
042			_adc
100	1		_aGiuseppe Pignataro _4auth
245	1	0	_aMechanisms of Innate Neuroprotection
260			_bFrontiers Media SA _c2016
300			_a1 electronic resource (138 p.)
506	0		_aOpen Access _2star _fUnrestricted online access
520			_aAs clinical trials of pharmacological neuroprotective strategies in stroke have been disappointing, attention has turned to the brain's own endogenous strategies for neuroprotection. Two endogenous mechanisms have been recently characterized, ischemic preconditioning and ischemic postconditioning. In the present topic newly characterized mechanisms involved in preconditioning- and postconditioning- neuroprotection will be discussed. The understanding of the mechanisms involved in the neuroprotective pathways induced by preconditioning and postconditioning will be clinically relevant for identifying new druggable target for neurodegenerative disorder therapy. Furthermore, the importance of these neuroprotective strategies resides in that it might be easily translatable into clinical practice. Therefore, the data presented here will highlight the capacity of ischemic preconditioning and postconditioning to be of benefit to humans.
540			_aCreative Commons _fhttps://creativecommons.org/licenses/by/4.0/ _2cc _4https://creativecommons.org/licenses/by/4.0/
546			_aEnglish
653			_aNeuroprotection
653			_apostconditioning
653			_aNCX
653			_aStroke
653			_aseizure
653			_amiRNA
653			_aAlzheimer
653			_apreconditioning
856	4	0	_awww.oapen.org _uhttp://journal.frontiersin.org/researchtopic/2693/mechanisms-of-innate-neuroprotection _70 _zDOAB: download the publication
856	4	0	_awww.oapen.org _uhttps://directory.doabooks.org/handle/20.500.12854/52944 _70 _zDOAB: description of the publication
999			_c48206 _d48206