000 02253naaaa2200301uu 4500
001 https://directory.doabooks.org/handle/20.500.12854/65137
005 20220219223910.0
020 _a876
020 _a9789533073750
020 _a9789535164838
024 7 _a10.5772/876
_cdoi
041 0 _aEnglish
042 _adc
072 7 _aMJG
_2bicssc
100 1 _aTonino, Paola
_4edt
700 1 _aTonino, Paola
_4oth
245 1 0 _aGastritis and Gastric Cancer : New Insights in Gastroprotection, Diagnosis and Treatments
260 _bIntechOpen
_c2011
300 _a1 electronic resource (310 p.)
506 0 _aOpen Access
_2star
_fUnrestricted online access
520 _aThis book is a comprehensive overview of invited contributions on Helicobacter pylori infection in gastritis and gastric carcinogenesis. The first part of the book covers topics related to the pathophysiology of gastric mucosal defense system and gastritis including the gastroprotective function of the mucus, the capsaicin-sensitive afferent nerves and the oxidative stress pathway involved in inflammation, apoptosis and autophagy in H. pylori related gastritis. The next chapters deal with molecular pathogenesis and treatment, which consider the role of neuroendocrine cells in gastric disease, DNA methylation in H. pylori infection, the role of antioxidants and phytotherapy in gastric disease. The final part presents the effects of cancer risk factors associated with H. pylori infection. These chapters discuss the serum pepsinogen test, K-ras mutations, cell kinetics, and H. pylori lipopolysaccharide, as well as the roles of several bacterial genes (cagA, cagT, vacA and dupA) as virulence factors in gastric cancer, and the gastrokine-1 protein in cancer progression.
540 _aCreative Commons
_fhttps://creativecommons.org/licenses/by-nc-sa/3.0/
_2cc
_4https://creativecommons.org/licenses/by-nc-sa/3.0/
546 _aEnglish
650 7 _aEndocrinology
_2bicssc
653 _aHepatology
856 4 0 _awww.oapen.org
_uhttps://mts.intechopen.com/storage/books/351/authors_book/authors_book.pdf
_70
_zDOAB: download the publication
856 4 0 _awww.oapen.org
_uhttps://directory.doabooks.org/handle/20.500.12854/65137
_70
_zDOAB: description of the publication
999 _c48536
_d48536