000			01947naaaa2200313uu 4500
001			https://directory.doabooks.org/handle/20.500.12854/42712
005			20220220043325.0
020			_a978-2-88945-331-3
020			_a9782889453313
024	7		_a10.3389/978-2-88945-331-3 _cdoi
041	0		_aEnglish
042			_adc
100	1		_aLeonardo Roever _4auth
700	1		_aAntonio C. Palandri Chagas _4auth
245	1	0	_aCardiac Remodeling: New Insights in Physiological and Pathological Adaptations
260			_bFrontiers Media SA _c2017
300			_a1 electronic resource (117 p.)
506	0		_aOpen Access _2star _fUnrestricted online access
520			_aThe effective management of Cardiac remodeling(CR), remains a major challenge. Heart failure remains the leading cause of death in industrialized countries. Yet, despite the enormity of the problem, effective therapeutic interventions remain elusive. In fact, several initially promising agents were found to decrease mortality in patients recovering from myocardial infarction. Cardiac remodeling is defined as molecular and interstitial changes, manifested clinically by changes in size, mass , geometry and function of the heart in response to certain aggression. Initially, ventricular remodeling aims to maintain stable cardiac function in situations of aggression.
540			_aCreative Commons _fhttps://creativecommons.org/licenses/by/4.0/ _2cc _4https://creativecommons.org/licenses/by/4.0/
546			_aEnglish
653			_aFibrosis
653			_aHeart Failure
653			_aPhysiology
653			_aInflammation
653			_aCardiac Remodeling
856	4	0	_awww.oapen.org _uhttps://www.frontiersin.org/research-topics/2942/cardiac-remodeling-new-insights-in-physiological-and-pathological-adaptations _70 _zDOAB: download the publication
856	4	0	_awww.oapen.org _uhttps://directory.doabooks.org/handle/20.500.12854/42712 _70 _zDOAB: description of the publication
999			_c65328 _d65328