000 02282naaaa2200313uu 4500
001 https://directory.doabooks.org/handle/20.500.12854/54879
005 20220220064419.0
020 _a9783110449501
020 _a9783110449501
020 _a9783110449617
024 7 _a10.1515/9783110449501
_cdoi
041 0 _aEnglish
042 _adc
100 1 _aHolban, Alina Maria
_4auth
700 1 _aGrumezescu, Alexandru Mihai
_4auth
245 1 0 _aNovel Molecular Approaches to Target Microbial Virulence
260 _bDe Gruyter
_c2015
300 _a1 electronic resource (87 p.)
506 0 _aOpen Access
_2star
_fUnrestricted online access
520 _aMicrobial infections still represent one of the major causes of mortality and morbidity worldwide. Irrational usage of antimicrobials has lead to increased resistance, causing clinical, social and economical disabilities. Therefore, one of the major challenges of scientists is to develop novel alternative methods to handle infections and reduce resistance and other side effects produced by the actual therapies. The aim of this book is to offer a perspective on novel approaches to handle infections by using naturally-derived products in order to modulate the virulence of pathogens, without the risk of developing resistance. We intend to highlight the utility of microbial, vegetal and animal–derived compounds with potential antimicrobial activity by exploiting their effect on microbial virulence. Furthermore, this book aims to reveal the potential to assimilate recent bio-technological findings, like the usage of nanotechnology as efficient shuttles for stabilizing, improved targeting and the controlled release of natural products in order to efficiently fight infections.
540 _aCreative Commons
_fhttps://creativecommons.org/licenses/by-nc-nd/4.0/
_2cc
_4https://creativecommons.org/licenses/by-nc-nd/4.0/
546 _aEnglish
653 _avirulence
653 _amolecular modulation
653 _aantimicrobial therapy
653 _adrug delivery nanoshuttles
856 4 0 _awww.oapen.org
_uhttps://doi.org/10.1515/9783110449501
_70
_zDOAB: download the publication
856 4 0 _awww.oapen.org
_uhttps://directory.doabooks.org/handle/20.500.12854/54879
_70
_zDOAB: description of the publication
999 _c71341
_d71341