| 000 | 04794naaaa2201333uu 4500 | ||
|---|---|---|---|
| 001 | https://directory.doabooks.org/handle/20.500.12854/76822 | ||
| 005 | 20220220070906.0 | ||
| 020 | _abooks978-3-0365-1607-3 | ||
| 020 | _a9783036516080 | ||
| 020 | _a9783036516073 | ||
| 024 | 7 |
_a10.3390/books978-3-0365-1607-3 _cdoi |
|
| 041 | 0 | _aEnglish | |
| 042 | _adc | ||
| 072 | 7 |
_aM _2bicssc |
|
| 100 | 1 |
_aMadureira, Patrícia Alexandra Saraiva _4edt |
|
| 700 | 1 |
_aMadureira, Patrícia Alexandra Saraiva _4oth |
|
| 245 | 1 | 0 | _aThe Shaping of Cancer by the Tumour Microenvironment and Its Relevance for Cancer Therapy |
| 260 |
_aBasel, Switzerland _bMDPI - Multidisciplinary Digital Publishing Institute _c2021 |
||
| 300 | _a1 electronic resource (307 p.) | ||
| 506 | 0 |
_aOpen Access _2star _fUnrestricted online access |
|
| 520 | _aIn this book, we present a compilation of original research articles as well as review articles that are focused on improving our understanding of the molecular and cellular mechanisms by which cancer cells adapt to their microenvironment. These include the interplay between cancer cells and the surrounding microenvironmental cells (e.g., macrophages, tumor-infiltrating lymphocytes and myeloid cells) and microenvironmental environments (e.g., oxidative stress, pH, hypoxia) and the implications of this dynamic interaction to tumor radioresistance, chemoresistance, invasion and metastasis. Finally, the importance and relevance of these findings are translated to cancer therapy. | ||
| 540 |
_aCreative Commons _fhttps://creativecommons.org/licenses/by/4.0/ _2cc _4https://creativecommons.org/licenses/by/4.0/ |
||
| 546 | _aEnglish | ||
| 650 | 7 |
_aMedicine _2bicssc |
|
| 653 | _ahypoxia | ||
| 653 | _amacrophages | ||
| 653 | _acolon cancer | ||
| 653 | _atumor microenvironment | ||
| 653 | _aimmune cell infiltration | ||
| 653 | _aprognosis | ||
| 653 | _afeline mammary carcinoma | ||
| 653 | _aPD-1 | ||
| 653 | _aPD-L1 | ||
| 653 | _aCTLA-4 | ||
| 653 | _aTNF-α | ||
| 653 | _abiomarkers | ||
| 653 | _aimmunotherapy | ||
| 653 | _acancer | ||
| 653 | _ahistone modification | ||
| 653 | _ainhibitor | ||
| 653 | _aKDM5B | ||
| 653 | _amolecular docking | ||
| 653 | _arepurposing | ||
| 653 | _acancer acidity | ||
| 653 | _ahyperosmolarity | ||
| 653 | _across-presentation | ||
| 653 | _atumour microenvironment | ||
| 653 | _asyngeneic model | ||
| 653 | _aprostate cancer | ||
| 653 | _aradiotherapy | ||
| 653 | _apreclinical modelling | ||
| 653 | _amyeloid-derived suppressor cells | ||
| 653 | _abiomarker | ||
| 653 | _astroma | ||
| 653 | _acancer-associated fibroblast (CAF) | ||
| 653 | _aextracellular matrix (ECM) | ||
| 653 | _acytokine/chemokine | ||
| 653 | _agrowth factors | ||
| 653 | _apro- and anti-tumor immune cells | ||
| 653 | _aimmunomodulatory roles | ||
| 653 | _aradiotherapy dose fractionation | ||
| 653 | _aradioresistance | ||
| 653 | _aradiosensitivity | ||
| 653 | _abreast cancer | ||
| 653 | _aS100A10 (p11) | ||
| 653 | _atumor growth | ||
| 653 | _atumor progression | ||
| 653 | _ametastasis | ||
| 653 | _acarcinoma | ||
| 653 | _amammary gland | ||
| 653 | _atriple negative | ||
| 653 | _apre-metastatic niche | ||
| 653 | _apro-inflammatory cytokines | ||
| 653 | _aclinical trials | ||
| 653 | _aevolutionary therapy | ||
| 653 | _adarwinian evolution | ||
| 653 | _acancer cells subpopulations | ||
| 653 | _adiclofenac | ||
| 653 | _akoningic acid | ||
| 653 | _aspheroid | ||
| 653 | _a3D co-culture | ||
| 653 | _amicroenvironment | ||
| 653 | _aresistance | ||
| 653 | _amyeloid cells | ||
| 653 | _acancer development | ||
| 653 | _amolecular subtypes of pancreatic cancer | ||
| 653 | _achemotherapy response | ||
| 653 | _apancreatic stellate cells | ||
| 653 | _aregulatory T cells | ||
| 653 | _atumor-associated macrophages | ||
| 653 | _amyeloid derived suppressor cells | ||
| 653 | _aglioblastoma (GB) | ||
| 653 | _aHypoxia Inducible Factor (HIF) | ||
| 653 | _aglioma stem cells (GSC) | ||
| 653 | _aoxidative stress | ||
| 653 | _areactive oxygen species | ||
| 653 | _aplasmin | ||
| 653 | _aplasminogen | ||
| 653 | _aS100A10 | ||
| 653 | _auPA | ||
| 653 | _auPAR | ||
| 653 | _aPAI-1 | ||
| 653 | _aPAI-2 | ||
| 653 | _acancer stem cells | ||
| 653 | _acancer recurrence | ||
| 653 | _atherapeutic resistance | ||
| 653 | _asignaling pathways | ||
| 653 | _atargeted therapy | ||
| 653 | _ahead and neck cancer | ||
| 653 | _alung cancer | ||
| 653 | _abladder cancer | ||
| 856 | 4 | 0 |
_awww.oapen.org _uhttps://mdpi.com/books/pdfview/book/4271 _70 _zDOAB: download the publication |
| 856 | 4 | 0 |
_awww.oapen.org _uhttps://directory.doabooks.org/handle/20.500.12854/76822 _70 _zDOAB: description of the publication |
| 999 |
_c72417 _d72417 |
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