| 000 | 02279naaaa2200337uu 4500 | ||
|---|---|---|---|
| 001 | https://directory.doabooks.org/handle/20.500.12854/53807 | ||
| 005 | 20220220080742.0 | ||
| 020 | _aintechopen.75144 | ||
| 020 | _a9781838806972 | ||
| 020 | _a9781838806989 | ||
| 020 | _a9781838806965 | ||
| 024 | 7 |
_a10.5772/intechopen.75144 _cdoi |
|
| 041 | 0 | _aEnglish | |
| 042 | _adc | ||
| 100 | 1 |
_aAditi Singh _4auth |
|
| 700 | 1 |
_aMohammad W. Khan _4auth |
|
| 245 | 1 | 0 | _aModulating Gene Expression - Abridging the RNAi and CRISPR-Cas9 Technologies |
| 260 |
_bIntechOpen _c2019 |
||
| 300 | _a1 electronic resource (134 p.) | ||
| 506 | 0 |
_aOpen Access _2star _fUnrestricted online access |
|
| 520 | _aRNA interference (RNAi) is a widely used technology for gene silencing and has become a key tool in a myriad of research and lead discoveries. In recent years, the mechanism of RNAi agents has been well investigated, and the technique has been optimized for better effectiveness and safety. On the other hand, the clustered regularly interspaced short palindromic repeats (CRISPR)-associated Cas9/gRNA system is a recent, novel, targeted genome-editing technique derived from the bacterial immune system. Recent advances in gene-editing research and technologies have enabled the CRISPR Cas9 system to become a popular tool for sequence-specific gene editing to correct and modify eukaryotic systems. In this book, we will focus on the mechanisms, applications, regulations (their pros and cons), and various ways in which RNAi-based methods and CRIPSR-Cas9 technology have stimulated the modulation of gene expression, thereby making them a promising therapeutic tool to treat and prevent complex diseases and disorders. | ||
| 540 |
_aAll rights reserved _4http://oapen.org/content/about-rights |
||
| 546 | _aEnglish | ||
| 653 | _aLife Sciences | ||
| 653 | _aMolecular Genetics | ||
| 653 | _aGenetics and Molecular Biology | ||
| 653 | _aGenomics | ||
| 653 | _aBiochemistry | ||
| 856 | 4 | 0 |
_awww.oapen.org _uhttps://www.intechopen.com/books/modulating-gene-expression-abridging-the-rnai-and-crispr-cas9-technologies _70 _zDOAB: download the publication |
| 856 | 4 | 0 |
_awww.oapen.org _uhttps://directory.doabooks.org/handle/20.500.12854/53807 _70 _zDOAB: description of the publication |
| 999 |
_c75062 _d75062 |
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