| 000 | 04349naaaa2201069uu 4500 | ||
|---|---|---|---|
| 001 | https://directory.doabooks.org/handle/20.500.12854/45509 | ||
| 005 | 20220220081904.0 | ||
| 020 | _abooks978-3-03897-917-3 | ||
| 020 | _a9783038979166 | ||
| 020 | _a9783038979173 | ||
| 024 | 7 |
_a10.3390/books978-3-03897-917-3 _cdoi |
|
| 041 | 0 | _aEnglish | |
| 042 | _adc | ||
| 100 | 1 |
_aLee, Hye Suk _4auth |
|
| 700 | 1 |
_aLiu, Kwang-Hyeon _4auth |
|
| 245 | 1 | 0 | _aDrug Metabolism, Pharmacokinetics and Bioanalysis |
| 260 |
_bMDPI - Multidisciplinary Digital Publishing Institute _c2019 |
||
| 300 | _a1 electronic resource (230 p.) | ||
| 506 | 0 |
_aOpen Access _2star _fUnrestricted online access |
|
| 520 | _aDrug metabolism/pharmacokinetics and drug interaction studies have been extensively carried out in order to secure the druggability and safety of new chemical entities throughout the development of new drugs. Recently, drug metabolism and transport by phase II drug metabolizing enzymes and drug transporters, respectively, as well as phase I drug metabolizing enzymes, have been studied. A combination of biochemical advances in the function and regulation of drug metabolizing enzymes and automated analytical technologies are revolutionizing drug metabolism research. There are also potential drug–drug interactions with co-administered drugs due to inhibition and/or induction of drug metabolic enzymes and drug transporters. In addition, drug interaction studies have been actively performed to develop substrate cocktails that do not interfere with each other and a simultaneous analytical method of substrate drugs and their metabolites using a tandem mass spectrometer. This Special Issue has the aim of highlighting current progress in drug metabolism/pharmacokinetics, drug interactions, and bioanalysis. | ||
| 540 |
_aCreative Commons _fhttps://creativecommons.org/licenses/by-nc-nd/4.0/ _2cc _4https://creativecommons.org/licenses/by-nc-nd/4.0/ |
||
| 546 | _aEnglish | ||
| 653 | _ahuman liver microsomes | ||
| 653 | _aalcohol addiction | ||
| 653 | _aUGT | ||
| 653 | _aultra-high-pressure liquid chromatography | ||
| 653 | _aadalimumab | ||
| 653 | _aprocainamide | ||
| 653 | _aLC-MS/MS | ||
| 653 | _aDA-9805 | ||
| 653 | _apaeonol | ||
| 653 | _aLC-QTOF-MS/MS | ||
| 653 | _aYRA-1909 | ||
| 653 | _achlorogenic acid | ||
| 653 | _aimmunoprecipitation | ||
| 653 | _aEurycoma longifolia | ||
| 653 | _aCYP | ||
| 653 | _acaffeic acid | ||
| 653 | _arat | ||
| 653 | _apharmaceutical excipient | ||
| 653 | _aKorean red ginseng extract | ||
| 653 | _aStauntonia hexaphylla leaf extract | ||
| 653 | _abioanalysis | ||
| 653 | _aHPLC-MS/MS | ||
| 653 | _aB6 | ||
| 653 | _aeurycomanone | ||
| 653 | _abioavailability | ||
| 653 | _adrying technology | ||
| 653 | _aGB3 | ||
| 653 | _adiclofenac | ||
| 653 | _a129-Glatm1Kul/J | ||
| 653 | _aaglycone | ||
| 653 | _acaffeic acid O-glucuronides | ||
| 653 | _aorganic anion transporting polypeptide | ||
| 653 | _aprotein precipitation | ||
| 653 | _ametabolic stability | ||
| 653 | _aFabry disease | ||
| 653 | _abiopharmaceuticals | ||
| 653 | _aimperatorin | ||
| 653 | _aneochlorogenic acid | ||
| 653 | _agastric ulcer | ||
| 653 | _asaikosaponin a | ||
| 653 | _ahair | ||
| 653 | _aanthraquinone | ||
| 653 | _aacetyl tributyl citrate | ||
| 653 | _apharmacokinetics | ||
| 653 | _abrain distribution | ||
| 653 | _amematine | ||
| 653 | _aethyl glucuronide | ||
| 653 | _apharmacokinetic | ||
| 653 | _aloxoprofen | ||
| 653 | _aliquid chromatography-quadrupole TOF MS | ||
| 653 | _aglucuronidation | ||
| 653 | _aesomeprazole | ||
| 653 | _ametformin | ||
| 653 | _acytochrome P450 | ||
| 653 | _aglycoside | ||
| 653 | _aAUDIT score | ||
| 653 | _aprotein stability | ||
| 653 | _aefficacy | ||
| 653 | _aLC-HR/MS | ||
| 653 | _acryptochlorogenic acid | ||
| 653 | _aaceclofenac | ||
| 653 | _adrug interaction | ||
| 653 | _aliquid chromatography-tandem mass spectrometry | ||
| 653 | _aOsthenol | ||
| 653 | _aplasma | ||
| 653 | _aN-acetylprocainamide | ||
| 653 | _adiabetes | ||
| 856 | 4 | 0 |
_awww.oapen.org _uhttps://mdpi.com/books/pdfview/book/1337 _70 _zDOAB: download the publication |
| 856 | 4 | 0 |
_awww.oapen.org _uhttps://directory.doabooks.org/handle/20.500.12854/45509 _70 _zDOAB: description of the publication |
| 999 |
_c75566 _d75566 |
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