| 000 | 02648naaaa2200349uu 4500 | ||
|---|---|---|---|
| 001 | https://directory.doabooks.org/handle/20.500.12854/49952 | ||
| 005 | 20220220082941.0 | ||
| 020 | _a978-2-88919-393-6 | ||
| 020 | _a9782889193936 | ||
| 024 | 7 |
_a10.3389/978-2-88919-393-6 _cdoi |
|
| 041 | 0 | _aEnglish | |
| 042 | _adc | ||
| 100 | 1 |
_aCarole Escartin _4auth |
|
| 700 | 1 |
_aKeith Murai _4auth |
|
| 245 | 1 | 0 | _aImaging and monitoring astrocytes in health and disease |
| 260 |
_bFrontiers Media SA _c2014 |
||
| 300 | _a1 electronic resource (189 p.) | ||
| 506 | 0 |
_aOpen Access _2star _fUnrestricted online access |
|
| 520 | _aAstrocytes are key cellular partners to neurons in the brain. They play an important role in multiple processes such as neurotransmitter recycling, trophic support, antioxidant defense, ionic homeostasis, inflammatory modulation, neurovascular and neurometabolic coupling, neurogenesis, synapse formation and synaptic plasticity. In addition to their crucial involvement in normal brain physiology, it is well known that astrocytes adopt a reactive phenotype under most acute and chronic pathological conditions such as ischemia, trauma, brain cancer, epilepsy, demyelinating and neurodegenerative diseases. However, the functional impact of astrocyte reactivity is still unclear. During the last decades, the development of innovative approaches to study astrocytes has significantly improved our understanding of their prominent role in brain function and their contribution to disease states. In particular, new genetic tools, molecular probes, and imaging techniques that achieve high spatial and temporal resolution have revealed new insight into astrocyte functions in situ. This Research Topic provides a collection of cutting-edge techniques, approaches and models to study astrocytes in health and disease. It also suggests new directions to achieve discoveries on these fascinating cells. | ||
| 540 |
_aCreative Commons _fhttps://creativecommons.org/licenses/by/4.0/ _2cc _4https://creativecommons.org/licenses/by/4.0/ |
||
| 546 | _aEnglish | ||
| 653 | _abrain imaging | ||
| 653 | _atransgenesis | ||
| 653 | _ahigh-resolution imaging | ||
| 653 | _agene transfer | ||
| 653 | _aReactive astrocytes | ||
| 653 | _aElectrophysiology | ||
| 653 | _aneuron-astrocyte interactions | ||
| 653 | _aIn vivo analysis | ||
| 856 | 4 | 0 |
_awww.oapen.org _uhttp://journal.frontiersin.org/researchtopic/1056/imaging-and-monitoring-astrocytes-in-health-and-disease _70 _zDOAB: download the publication |
| 856 | 4 | 0 |
_awww.oapen.org _uhttps://directory.doabooks.org/handle/20.500.12854/49952 _70 _zDOAB: description of the publication |
| 999 |
_c76042 _d76042 |
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