000 02090naaaa2200313uu 4500
001 https://directory.doabooks.org/handle/20.500.12854/67635
005 20220220091102.0
020 _aintechopen.82965
020 _a9781838801267
020 _a9781838801250
020 _a9781839680182
024 7 _a10.5772/intechopen.82965
_cdoi
041 0 _aEnglish
042 _adc
072 7 _aPSBC
_2bicssc
100 1 _aDulce Bagatini, Margarete
_4edt
700 1 _aDulce Bagatini, Margarete
_4oth
245 1 0 _aGlutathione System and Oxidative Stress in Health and Disease
260 _bIntechOpen
_c2020
300 _a1 electronic resource (138 p.)
506 0 _aOpen Access
_2star
_fUnrestricted online access
520 _aThe imbalance between the production of reactive oxygen species (ROS) and antioxidant defenses determines a state known as oxidative stress. Higher levels of pro-oxidants compared to antioxidant defenses may generate oxidative damage, which, in turn, may lead to modifications in cellular proteins, lipids, and DNA, reducing functional capacity and increasing the risk of diseases. Nevertheless, the clearance of harmful reactive chemical species is achieved by the antioxidant defense systems. These protection systems are referred to as the first and second lines of defense and comprise the classic antioxidants, enzymatic and nonenzymatic defenses, including glutathione. This book presents and discusses the advancement of research on health and diseases and their underlying mechanisms, exploring mainly aspects related to the glutathione antioxidant system.
540 _aCreative Commons
_fhttps://creativecommons.org/licenses/by/3.0/
_2cc
_4https://creativecommons.org/licenses/by/3.0/
546 _aEnglish
650 7 _aProteins
_2bicssc
653 _aCellular biology (cytology)
856 4 0 _awww.oapen.org
_uhttps://mts.intechopen.com/storage/books/9002/authors_book/authors_book.pdf
_70
_zDOAB: download the publication
856 4 0 _awww.oapen.org
_uhttps://directory.doabooks.org/handle/20.500.12854/67635
_70
_zDOAB: description of the publication
999 _c77870
_d77870