| 000 | 02299naaaa2200277uu 4500 | ||
|---|---|---|---|
| 001 | https://directory.doabooks.org/handle/20.500.12854/41759 | ||
| 005 | 20220220091415.0 | ||
| 020 | _a9783038429739 | ||
| 020 | _a9783038429746 | ||
| 041 | 0 | _aEnglish | |
| 042 | _adc | ||
| 100 | 1 |
_aKristina Pentieva (Ed.) _4auth |
|
| 245 | 1 | 0 | _aB-Vitamins and One-Carbon Metabolism |
| 260 |
_bMDPI - Multidisciplinary Digital Publishing Institute _c2018 |
||
| 300 | _a1 electronic resource (XII, 390 p.) | ||
| 506 | 0 |
_aOpen Access _2star _fUnrestricted online access |
|
| 520 | _aFolate, vitamin B12, vitamin B6 and riboflavin play a key role as coenzymes in one-carbon metabolism which, in turn, is essential for a broad range of fundamental physiological processes, including RNA and DNA synthesis, cell division, tissue growth and methylation. Deficiencies or imbalance of B-vitamins, as well as genetic polymorphisms and environmental factors, are shown to disturb the normal function of one-carbon metabolism with adverse effects on human health. Although a vast volume of research has already been conducted in this area, there are still significant gaps in our knowledge that require further investigations. This Special Issue of Nutrients invited submission of manuscripts, original research or reviews of the scientific literature, focused on novel findings in relation to B-vitamins and one-carbon metabolism in terms of: metabolic roles and molecular mechanisms; gene–nutrient interactions; fetal growth and programing; risk of disease (birth defects and pregnancy related conditions, cancer, cardiovascular disease and hypertension, neuropsychiatric disease, osteoporosis); health effects of B-vitamin supplementation and food fortification. | ||
| 540 |
_aCreative Commons _fhttps://creativecommons.org/licenses/by-nc-nd/4.0/ _2cc _4https://creativecommons.org/licenses/by-nc-nd/4.0/ |
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| 546 | _aEnglish | ||
| 653 | _aB-vitamins and DNA methylation | ||
| 653 | _aB-vitamins | ||
| 653 | _aOne-carbon metabolism | ||
| 653 | _aB-vitamins and risk of disease | ||
| 856 | 4 | 0 |
_awww.oapen.org _uhttp://www.mdpi.com/books/pdfview/book/650 _70 _zDOAB: download the publication |
| 856 | 4 | 0 |
_awww.oapen.org _uhttps://directory.doabooks.org/handle/20.500.12854/41759 _70 _zDOAB: description of the publication |
| 999 |
_c78012 _d78012 |
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