| 000 | 05270naaaa2201309uu 4500 | ||
|---|---|---|---|
| 001 | https://directory.doabooks.org/handle/20.500.12854/40131 | ||
| 005 | 20220220092036.0 | ||
| 020 | _abooks978-3-03928-587-7 | ||
| 020 | _a9783039285860 | ||
| 020 | _a9783039285877 | ||
| 024 | 7 |
_a10.3390/books978-3-03928-587-7 _cdoi |
|
| 041 | 0 | _aEnglish | |
| 042 | _adc | ||
| 100 | 1 |
_aBüchler, Christa _4auth |
|
| 245 | 1 | 0 | _aAdipokines 2.0 |
| 260 |
_bMDPI - Multidisciplinary Digital Publishing Institute _c2020 |
||
| 300 | _a1 electronic resource (406 p.) | ||
| 506 | 0 |
_aOpen Access _2star _fUnrestricted online access |
|
| 520 | _aOnce viewed solely as fat storage cells, adipocytes and their adipokines have now been proven to be central for human health. Understanding that overweight and obesity may increase the risk for various diseases requires detailed characterization of adipokine function. Weight gain, weight regain, and fasting affect adipocyte health and accordingly their secretome. Different adipose tissue deposits exist and they vary in cellular composition and function. The evidence is strong of a role of adipokines in cancer, reproductive function, neurological diseases, cardiovascular diseases ,and rheumatoid arthritis. Adipokines are considered useful biomarkers for adipose tissue and metabolic health, and may be used as diagnostic tools in rheumatoid arthritis, cancer, or sepsis. This book contains 10 original articles and 9 review articles focusing on these bioactive peptides. Several articles deal with chemerin, an adipokine discovered more than 20 years ago. Data so far have resulted in promising insights related to its biological function. We are only beginning to understand the multiple roles of chemerin, the mechanisms regulating its activity, and the signaling pathways used by this chemokine. Adipokine receptor agonists and antagonists may result in the formulation of novel drugs and ultimately may lead to new therapeutic targets to be used in clinical practice. | ||
| 540 |
_aCreative Commons _fhttps://creativecommons.org/licenses/by-nc-nd/4.0/ _2cc _4https://creativecommons.org/licenses/by-nc-nd/4.0/ |
||
| 546 | _aEnglish | ||
| 653 | _an/a | ||
| 653 | _alipids | ||
| 653 | _acathepsins | ||
| 653 | _aneurodegeneration | ||
| 653 | _atocilizumab | ||
| 653 | _aSGBS adipocytes | ||
| 653 | _achemerin receptors | ||
| 653 | _acholesterol | ||
| 653 | _ametabolically healthy obese | ||
| 653 | _aenergy metabolism | ||
| 653 | _aadipose-brain axis | ||
| 653 | _aEP3 receptor | ||
| 653 | _aleptin | ||
| 653 | _arheumatoid arthritis | ||
| 653 | _aexcessive gestational weight gain | ||
| 653 | _ain vitro fat regain | ||
| 653 | _asecreted frizzled-related protein 5 | ||
| 653 | _aPCOS | ||
| 653 | _aEP4 receptor | ||
| 653 | _aleukocyte | ||
| 653 | _aexchange protein directly activated by cAMP isoform 2 (EPAC2) | ||
| 653 | _aextracellular remodeling | ||
| 653 | _ainsulin | ||
| 653 | _aosteoarthritis | ||
| 653 | _alipid metabolism | ||
| 653 | _afat mass | ||
| 653 | _aTango bioassay | ||
| 653 | _afatty liver | ||
| 653 | _afree fatty acids | ||
| 653 | _alabel-free proteomic profiling | ||
| 653 | _ainterleukin(IL)-33 | ||
| 653 | _asick fat | ||
| 653 | _apolycystic ovary syndrome | ||
| 653 | _aearly-life programming | ||
| 653 | _ainflammation | ||
| 653 | _agestational diabetes | ||
| 653 | _aglucose restriction | ||
| 653 | _aadipokines | ||
| 653 | _aneonatal anthropometry | ||
| 653 | _aepicardial adipose tissue (EAT) | ||
| 653 | _aoestrous cycle | ||
| 653 | _aCardiovascular Diseases (CVDs) | ||
| 653 | _atriglycerides | ||
| 653 | _aG protein-coupled receptor 1 | ||
| 653 | _atesticular pathologies | ||
| 653 | _aprognosis | ||
| 653 | _aovary | ||
| 653 | _aICU | ||
| 653 | _abiologic activity | ||
| 653 | _apreeclempsia | ||
| 653 | _aadipokine | ||
| 653 | _acritical illness | ||
| 653 | _aearly pregnancy | ||
| 653 | _amyokine | ||
| 653 | _aliver steatosis | ||
| 653 | _aC-C chemokine receptor-like 2 | ||
| 653 | _atestis | ||
| 653 | _astimulating growth factor 2 (ST2) | ||
| 653 | _apig | ||
| 653 | _afitness | ||
| 653 | _ahuman granulosa cells | ||
| 653 | _aobesity | ||
| 653 | _aproteolysis | ||
| 653 | _aannexins | ||
| 653 | _aadipose tissue | ||
| 653 | _abiomarker | ||
| 653 | _aghrelin | ||
| 653 | _abrain health | ||
| 653 | _asepsis | ||
| 653 | _aadiponectin | ||
| 653 | _arheumatic diseases | ||
| 653 | _achemokine-like receptor 1 | ||
| 653 | _afollicular fluid | ||
| 653 | _aglucose homeostasis | ||
| 653 | _aresistin | ||
| 653 | _aNonalcoholic fatty liver disease | ||
| 653 | _aprostaglandin E2 (PGE2) | ||
| 653 | _avisceral fat | ||
| 653 | _amicroglia | ||
| 653 | _aweight regain | ||
| 653 | _acomplement factors | ||
| 653 | _aalpha-fetoprotein | ||
| 653 | _apolycystic ovary morphology | ||
| 653 | _achemerin | ||
| 653 | _acancer | ||
| 653 | _adepression | ||
| 653 | _ahypertension | ||
| 653 | _ahypothalamus | ||
| 856 | 4 | 0 |
_awww.oapen.org _uhttps://mdpi.com/books/pdfview/book/2157 _70 _zDOAB: download the publication |
| 856 | 4 | 0 |
_awww.oapen.org _uhttps://directory.doabooks.org/handle/20.500.12854/40131 _70 _zDOAB: description of the publication |
| 999 |
_c78308 _d78308 |
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