000 03771naaaa2200925uu 4500
001 https://directory.doabooks.org/handle/20.500.12854/69447
005 20220220092236.0
020 _abooks978-3-03943-674-3
020 _a9783039436736
020 _a9783039436743
024 7 _a10.3390/books978-3-03943-674-3
_cdoi
041 0 _aEnglish
042 _adc
072 7 _aGP
_2bicssc
072 7 _aPS
_2bicssc
100 1 _aGovorunova, Elena G.
_4edt
700 1 _aSineshchekov, Oleg A.
_4edt
700 1 _aGovorunova, Elena G.
_4oth
700 1 _aSineshchekov, Oleg A.
_4oth
245 1 0 _aThe Advances and Applications of Optogenetics
260 _aBasel, Switzerland
_bMDPI - Multidisciplinary Digital Publishing Institute
_c2020
300 _a1 electronic resource (164 p.)
506 0 _aOpen Access
_2star
_fUnrestricted online access
520 _aThis book provides an update for the rapidly developing technology known as “optogenetics”, which is the use of genetically encoded light-sensitive molecular elements (usually derived from lower organisms) to control or report various physiological and biochemical processes within the cell. Two ongoing clinical trials use optogenetic tools for vision restoration, and optogenetic strategies have been suggested as novel therapies for several neurological, psychiatric and cardiac disorders. This Special Issue comprises two reviews and seven experimental papers on different types of light-sensitive modules widely used in optogenetic studies. These papers demonstrate the efficiency and versatility of optogenetics and are expected to be equally relevant for advanced users and beginners considering using optogenetic tools in their research.
540 _aCreative Commons
_fhttps://creativecommons.org/licenses/by/4.0/
_2cc
_4https://creativecommons.org/licenses/by/4.0/
546 _aEnglish
650 7 _aResearch & information: general
_2bicssc
650 7 _aBiology, life sciences
_2bicssc
653 _aoptogenetic tools
653 _aneuroscience
653 _acalcium sensor
653 _avoltage sensor
653 _aneurotransmitters
653 _aoptogenetics
653 _achannelrhodopsins
653 _asodium
653 _acalcium
653 _aDC gate
653 _aOptogenetics
653 _ap53
653 _aAsLOV2
653 _aLINuS
653 _aLEXY
653 _aMIP
653 _aPMI
653 _aChlamydomonas reinhardtii
653 _aion channel
653 _aelectrophysiology
653 _amolecular dynamics simulations
653 _amembrane-protein interaction
653 _aenergy of membrane deformation
653 _aCTMD method, residual hydrophobic mismatch
653 _amicrobial rhodopsin
653 _achannelrhodopsin
653 _amembrane current
653 _ahippocampal neurons
653 _alight stimulation
653 _achannelrhodopsin-2
653 _aphotoreceptor
653 _aBLUF
653 _amodular domain
653 _aresonance Raman
653 _aflash photolysis
653 _ahybrid QM/MM simulation
653 _atwo-photon
653 _aazobenzene
653 _aphotoswitch
653 _aphotoswitching
653 _aphotocontrol
653 _aall-optical electrophysiology
653 _amicrobial rhodopsins
653 _aion channels
653 _aLOV domains
653 _amembrane potential
653 _aintracellular trafficking
653 _aprotein–protein interaction
653 _asignaling
856 4 0 _awww.oapen.org
_uhttps://mdpi.com/books/pdfview/book/3251
_70
_zDOAB: download the publication
856 4 0 _awww.oapen.org
_uhttps://directory.doabooks.org/handle/20.500.12854/69447
_70
_zDOAB: description of the publication
999 _c78396
_d78396