000			03251naaaa2200349uu 4500
001			https://directory.doabooks.org/handle/20.500.12854/61903
005			20220220094539.0
020			_a978-2-88945-264-4
020			_a9782889452644
024	7		_a10.3389/978-2-88945-264-4 _cdoi
041	0		_aEnglish
042			_adc
100	1		_aGiovanni Biglino _4auth
700	1		_aAdelaide de Vecchi _4auth
245	1	0	_aVentricular Mechanics in Congenital Heart Disease
260			_bFrontiers Media SA _c2017
300			_a1 electronic resource (120 p.)
506	0		_aOpen Access _2star _fUnrestricted online access
520			_aLooking at "Horse in Motion", the iconic photograph by E. Muybridge, it is almost possible to hear the horse galloping. The pounding sound of the hoofs hitting the ground -like a drum- can also echo the rythmic beating of the human heart. That sound, that visceral rhythm, reminds us of the link between motion and performance: the perfectly executed stride of the horse, the incredible coordination of multiscale phenomena behind a heart beat. Furthermore, the decomposed sequence in Muybridge's photograph has become a well-known example of breaking motion into its components over time, and as such is reminiscent of those images that are routinely acquired in clinical practice, where the heart appears dilating and shirnking in a sequence of snapshots. The investigation of this motion and its subtleties is essential for refining our understanding of cardiac function, and the appreciation of how and when this motion is no longer perfectly executed can lead us to understand functional impairments and provide insight into the unfolding of pathology. In the presence of congenital heart disease (CHD), cardiac mechanics are altered: from single ventricle physiology to conduction abnormalities to different cardiomyopathies, it is important to both capture and interpret biomechanical changes that occur in the presence of a congenital defect. This special issue in Frontiers in Pediatrics, now an e-book, focuses on 'Ventricular mechanics in congenital heart disease' and looks at current knowledge of phenomena such as systolic/diastolic dysfuction and current methods (chiefly in cardiovascular magnetic resonance imaging and echocardiography) to evaluate cardiac function in the presence of CHD, and then presents a series of original studies that employ both medical imaging and computational modelling techniques to study specific CHD scenarios.
540			_aCreative Commons _fhttps://creativecommons.org/licenses/by/4.0/ _2cc _4https://creativecommons.org/licenses/by/4.0/
546			_aEnglish
653			_acardiovascular magnetic resonance imaging
653			_aventricular mechanics
653			_aCongenital Heart Diseases
653			_ahypoplastic left heart syndrome
653			_adiastolic function
653			_acomputational modelling
653			_asystolic function
653			_ahaemodynamics
856	4	0	_awww.oapen.org _uhttp://journal.frontiersin.org/researchtopic/4933/ventricular-mechanics-in-congenital-heart-disease _70 _zDOAB: download the publication
856	4	0	_awww.oapen.org _uhttps://directory.doabooks.org/handle/20.500.12854/61903 _70 _zDOAB: description of the publication
999			_c79434 _d79434