000 03661naaaa2200913uu 4500
001 https://directory.doabooks.org/handle/20.500.12854/57786
005 20220220095428.0
020 _abooks978-3-03921-502-7
020 _a9783039215010
020 _a9783039215027
024 7 _a10.3390/books978-3-03921-502-7
_cdoi
041 0 _aEnglish
042 _adc
100 1 _aKawakami, Kohsaku
_4auth
245 1 0 _aRecent Progress in Solid Dispersion Technology
260 _bMDPI - Multidisciplinary Digital Publishing Institute
_c2019
300 _a1 electronic resource (204 p.)
506 0 _aOpen Access
_2star
_fUnrestricted online access
520 _aAmorphous solid dispersion (ASD) is a powerful formulation technology to improve oral absorption of poorly soluble drugs. Despite their being in existence for more than half a century, controlling ASD performance is still regarded as difficult because of ASD’s natural non-equilibrium. However, recent significant advances in ASD knowledge and technology may enable a much broader use of ASD technology. This Special Issue, which includes 3 reviews and 6 original articles, focuses on recent progresses in ASD technology in hopes of helping to accelerate developmental studies in the pharmaceutical industry. In striving for a deep understanding of ASD non-equilibrium behavior, the Special issue also delves into and makes progress in the theory of soft-matter dynamics.
540 _aCreative Commons
_fhttps://creativecommons.org/licenses/by-nc-nd/4.0/
_2cc
_4https://creativecommons.org/licenses/by-nc-nd/4.0/
546 _aEnglish
653 _athermodynamic modeling
653 _amolecular dynamics simulation
653 _apoorly soluble drugs
653 _aamorphous solid dispersions
653 _adissolution enhancement
653 _acrystallization tendency
653 _acontinuous processing
653 _astability
653 _amilling
653 _agranulation
653 _athermal analysis
653 _aamorphous
653 _aball milling
653 _apharmaceutical glass
653 _adissolution
653 _arebamipide
653 _apoloxamer
653 _aclassification
653 _apolyelectrolytes
653 _aamorphisation
653 _aself-assembly
653 _adissolution rate
653 _amiscibility
653 _abioavailability
653 _asolubility
653 _aevaporation
653 _amesoporous
653 _apolyelectrolyte excipient matrix
653 _apolymer
653 _abicaludamide
653 _aphase diagram
653 _aWeibull dissolution model
653 _aspectroscopic techniques
653 _aanticancer drugs
653 _amanufacturing methods
653 _anucleation
653 _amolecular complex
653 _ananoaggregates
653 _aenrofloxacin
653 _aaccelerated stability test
653 _asolubility enhancement
653 _aamorphous solid dispersion
653 _atadalafil
653 _aprocess development
653 _aamorphous polymeric salt
653 _aWood’s apparatus
653 _ahot melt extrusion
653 _asolid dispersions
653 _aintrinsic dissolution rate
653 _asolid dispersion
653 _ainteraction
653 _acrystallization
653 _aspray drying
653 _acharacterization
653 _aciprofloxacin
856 4 0 _awww.oapen.org
_uhttps://mdpi.com/books/pdfview/book/1607
_70
_zDOAB: download the publication
856 4 0 _awww.oapen.org
_uhttps://directory.doabooks.org/handle/20.500.12854/57786
_70
_zDOAB: description of the publication
999 _c79821
_d79821