| 000 | 06537naaaa2201705uu 4500 | ||
|---|---|---|---|
| 001 | https://directory.doabooks.org/handle/20.500.12854/54359 | ||
| 005 | 20220220100825.0 | ||
| 020 | _abooks978-3-03928-747-5 | ||
| 020 | _a9783039287468 | ||
| 020 | _a9783039287475 | ||
| 024 | 7 |
_a10.3390/books978-3-03928-747-5 _cdoi |
|
| 041 | 0 | _aEnglish | |
| 042 | _adc | ||
| 100 | 1 |
_aAvato, Pinarosa _4auth |
|
| 245 | 1 | 0 | _aNatural Products and Drug Discovery |
| 260 |
_bMDPI - Multidisciplinary Digital Publishing Institute _c2020 |
||
| 300 | _a1 electronic resource (392 p.) | ||
| 506 | 0 |
_aOpen Access _2star _fUnrestricted online access |
|
| 520 | _aNatural products hold a prominent position in the current discovery and development of drugs and have diverse indications for both human and animal health. Plants, in particular, play a leading role as a source of specialized metabolites with medical effects. Other organisms, such as marine and terrestrial animals and microorganisms, produce very important drug candidate molecules. Specialized metabolites from these varied natural sources can be used directly as bioactive compounds or drug precursors. In addition, due to their broad chemical diversity, they can act as drug prototypes and/or be used as pharmacological tools for different targets. Some examples of natural metabolites that have been developed into useful medical drug are cardiotonic digoxin from Digitalis sp., antimalarial artemisinin from Artemisia annua, anti-cancer taxol from Taxus sp., or podophyllotoxin from Podophyllum peltatum, which served as a synthetic model for the anti-cancer etoposide. The study of natural products is still attracting great scientific attention and their current importance, as a valuable lead for drug discovery, is undebatable. I cordially invite authors to contribute original articles, as well as survey articles, that give the readers of Molecules **MOLECULES NEEDS TO BE ITALICIZED** updated and new perspectives on natural products in drug discovery, including but not limited to natural sources, identification and separation of bioactive phytochemicals, standardization, new biological targets, pre-clinical and clinical trials, pharmacological effects/side effects, and bioassays. | ||
| 540 |
_aCreative Commons _fhttps://creativecommons.org/licenses/by-nc-nd/4.0/ _2cc _4https://creativecommons.org/licenses/by-nc-nd/4.0/ |
||
| 546 | _aEnglish | ||
| 653 | _adihydrochalcones | ||
| 653 | _acytotoxicity-guided | ||
| 653 | _an/a | ||
| 653 | _aharpagoside | ||
| 653 | _abiotechnology | ||
| 653 | _asynergy | ||
| 653 | _aImperata cylindrica | ||
| 653 | _a5?-dimethylchalcone (DMC) | ||
| 653 | _aantioxidant activity | ||
| 653 | _amarine resources | ||
| 653 | _aphenolic derivatives | ||
| 653 | _asecondary metabolites | ||
| 653 | _aantimicrobial agents | ||
| 653 | _aantimicrobial resistance | ||
| 653 | _ametabolomics | ||
| 653 | _aHumulus lupulus | ||
| 653 | _achromatography | ||
| 653 | _astereochemistry | ||
| 653 | _aFSE | ||
| 653 | _acytokines | ||
| 653 | _acytotoxic activity | ||
| 653 | _aglutamate | ||
| 653 | _aangiogenesis | ||
| 653 | _atraditional medicine | ||
| 653 | _aCa2+ | ||
| 653 | _aL6 cell | ||
| 653 | _ahuman colon cancer cell lines | ||
| 653 | _asiphonous green algae | ||
| 653 | _aanti-inflammatory activity | ||
| 653 | _aPhyllanthus chamacristoides | ||
| 653 | _aspectroscopic analysis | ||
| 653 | _aPhyscomitrella patens | ||
| 653 | _aLeishmania mexicana mexicana | ||
| 653 | _adementia | ||
| 653 | _aprenylated phenolic compounds | ||
| 653 | _aT2DM | ||
| 653 | _aHPLC-ESI-microTOF-Q-MS/MS | ||
| 653 | _aEruca sativa | ||
| 653 | _aDryopteris fragrans | ||
| 653 | _achemosystematics | ||
| 653 | _a2? | ||
| 653 | _acerebellum | ||
| 653 | _aCleistocalyx operculatus | ||
| 653 | _ainflammation | ||
| 653 | _amultivariate data analysis | ||
| 653 | _aPhyllanthus orbicularis | ||
| 653 | _aHPLC | ||
| 653 | _acardiovascular disease | ||
| 653 | _aKv7 potassium channels | ||
| 653 | _amarine peptides | ||
| 653 | _aproliferation | ||
| 653 | _asulfated coumarins | ||
| 653 | _aOrobanche s.l. | ||
| 653 | _aphenylpropanoid glycosides | ||
| 653 | _aHarpagophytum procumbens | ||
| 653 | _asesquiterpenoids | ||
| 653 | _aTRPV1 | ||
| 653 | _aFideloside | ||
| 653 | _aphenylethanoid glycosides | ||
| 653 | _aCuba | ||
| 653 | _amolecular network | ||
| 653 | _aNMR | ||
| 653 | _aketamine | ||
| 653 | _aaging | ||
| 653 | _aGLUT4 | ||
| 653 | _adiabetes | ||
| 653 | _aoxidative stress | ||
| 653 | _aLamiales | ||
| 653 | _acircular dichroism | ||
| 653 | _apsychosis | ||
| 653 | _aantinociceptive | ||
| 653 | _aimmuno-regulation activity | ||
| 653 | _aterpenoids | ||
| 653 | _aNADPH oxidases | ||
| 653 | _adiabetic neuropathy | ||
| 653 | _aspagyric tincture | ||
| 653 | _aH2S | ||
| 653 | _acelastrol | ||
| 653 | _aisolation and quantification | ||
| 653 | _a4?-dihydroxy-6?-methoxy-3? | ||
| 653 | _aLeea indica | ||
| 653 | _aC-glycoside | ||
| 653 | _aneuropathic pain | ||
| 653 | _aPANC-1 | ||
| 653 | _aglucosinolates | ||
| 653 | _aflavonoids | ||
| 653 | _abioactivities of natural products | ||
| 653 | _acardamonin | ||
| 653 | _aisoflavones | ||
| 653 | _aterpenes | ||
| 653 | _amethicillin-resistant Staphylococcus aureus | ||
| 653 | _amalaria | ||
| 653 | _aartemisinin | ||
| 653 | _anatural products | ||
| 653 | _adevil’s claw | ||
| 653 | _aACE inhibitory peptide | ||
| 653 | _apPancreatic cancer | ||
| 653 | _agrowth inhibitory activity | ||
| 653 | _amass spectrometry | ||
| 653 | _aflavonoid | ||
| 653 | _aphenolics | ||
| 653 | _aAstragalus boeticus L. | ||
| 653 | _aproanthocyanidins | ||
| 653 | _aopioid | ||
| 653 | _aTrifolium | ||
| 653 | _aTrypanosoma brucei brucei | ||
| 653 | _aacetylated astragalosides | ||
| 653 | _aFabaceae | ||
| 653 | _abioactive peptides | ||
| 653 | _aLC-MS | ||
| 653 | _aDasycladus vermicularis | ||
| 653 | _aOrobanchaceae | ||
| 653 | _amigration | ||
| 653 | _aglucoerucin | ||
| 653 | _aESI-MS/MS | ||
| 653 | _acancer | ||
| 653 | _azebrafish | ||
| 653 | _aantihypertensive | ||
| 653 | _aBacopa monnieri | ||
| 653 | _achemical derivatization | ||
| 653 | _ahypertension | ||
| 856 | 4 | 0 |
_awww.oapen.org _uhttps://mdpi.com/books/pdfview/book/2231 _70 _zDOAB: download the publication |
| 856 | 4 | 0 |
_awww.oapen.org _uhttps://directory.doabooks.org/handle/20.500.12854/54359 _70 _zDOAB: description of the publication |
| 999 |
_c80415 _d80415 |
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