Entwicklung eines mikrofluidischen Zweikammer-Chipsystems mit integrierter Sensorik für die Anwendung in der Tumorforschung
Rajabi, Taleieh
Entwicklung eines mikrofluidischen Zweikammer-Chipsystems mit integrierter Sensorik für die Anwendung in der Tumorforschung - KIT Scientific Publishing 2014 - 1 electronic resource (IX, 163 p. p.)
Open Access
We have developed a microfluidic two-layered channel system based on polycarbonate to investigate the transmigration of cancer cells under flow conditions and defined shear rate using live cell microscopy. The two layers are separated by a porous membrane with an endothelial monolayer on top of the membrane to mimic the blood vessel wall. To extend the measuring capabilities of our microfluidic chip, gold electrodes were structured on the membrane using optical lithography and chemical etching.
Creative Commons
German
KSP/1000041112 9783731502203
10.5445/KSP/1000041112 doi
membrane Krebszellen SensorikCancer cell Metastasierung Mikrofluidik Blutgefäß sensors Membran Blood vessel Impedanz microfluidic Impedance
Entwicklung eines mikrofluidischen Zweikammer-Chipsystems mit integrierter Sensorik für die Anwendung in der Tumorforschung - KIT Scientific Publishing 2014 - 1 electronic resource (IX, 163 p. p.)
Open Access
We have developed a microfluidic two-layered channel system based on polycarbonate to investigate the transmigration of cancer cells under flow conditions and defined shear rate using live cell microscopy. The two layers are separated by a porous membrane with an endothelial monolayer on top of the membrane to mimic the blood vessel wall. To extend the measuring capabilities of our microfluidic chip, gold electrodes were structured on the membrane using optical lithography and chemical etching.
Creative Commons
German
KSP/1000041112 9783731502203
10.5445/KSP/1000041112 doi
membrane Krebszellen SensorikCancer cell Metastasierung Mikrofluidik Blutgefäß sensors Membran Blood vessel Impedanz microfluidic Impedance