Modulating Gene Expression - Abridging the RNAi and CRISPR-Cas9 Technologies (Record no. 75062)

MARC details
000 -LEADER
fixed length control field 02279naaaa2200337uu 4500
001 - CONTROL NUMBER
control field https://directory.doabooks.org/handle/20.500.12854/53807
005 - DATE AND TIME OF LATEST TRANSACTION
control field 20220220080742.0
020 ## - INTERNATIONAL STANDARD BOOK NUMBER
International Standard Book Number intechopen.75144
020 ## - INTERNATIONAL STANDARD BOOK NUMBER
International Standard Book Number 9781838806972
020 ## - INTERNATIONAL STANDARD BOOK NUMBER
International Standard Book Number 9781838806989
020 ## - INTERNATIONAL STANDARD BOOK NUMBER
International Standard Book Number 9781838806965
024 7# - OTHER STANDARD IDENTIFIER
Standard number or code 10.5772/intechopen.75144
Terms of availability doi
041 0# - LANGUAGE CODE
Language code of text/sound track or separate title English
042 ## - AUTHENTICATION CODE
Authentication code dc
100 1# - MAIN ENTRY--PERSONAL NAME
Personal name Aditi Singh
Relationship auth
245 10 - TITLE STATEMENT
Title Modulating Gene Expression - Abridging the RNAi and CRISPR-Cas9 Technologies
260 ## - PUBLICATION, DISTRIBUTION, ETC.
Name of publisher, distributor, etc. IntechOpen
Date of publication, distribution, etc. 2019
300 ## - PHYSICAL DESCRIPTION
Extent 1 electronic resource (134 p.)
506 0# - RESTRICTIONS ON ACCESS NOTE
Terms governing access Open Access
Source of term star
Standardized terminology for access restriction Unrestricted online access
520 ## - SUMMARY, ETC.
Summary, etc. RNA interference (RNAi) is a widely used technology for gene silencing and has become a key tool in a myriad of research and lead discoveries. In recent years, the mechanism of RNAi agents has been well investigated, and the technique has been optimized for better effectiveness and safety. On the other hand, the clustered regularly interspaced short palindromic repeats (CRISPR)-associated Cas9/gRNA system is a recent, novel, targeted genome-editing technique derived from the bacterial immune system. Recent advances in gene-editing research and technologies have enabled the CRISPR Cas9 system to become a popular tool for sequence-specific gene editing to correct and modify eukaryotic systems. In this book, we will focus on the mechanisms, applications, regulations (their pros and cons), and various ways in which RNAi-based methods and CRIPSR-Cas9 technology have stimulated the modulation of gene expression, thereby making them a promising therapeutic tool to treat and prevent complex diseases and disorders.
540 ## - TERMS GOVERNING USE AND REPRODUCTION NOTE
Terms governing use and reproduction All rights reserved
-- http://oapen.org/content/about-rights
546 ## - LANGUAGE NOTE
Language note English
653 ## - INDEX TERM--UNCONTROLLED
Uncontrolled term Life Sciences
653 ## - INDEX TERM--UNCONTROLLED
Uncontrolled term Molecular Genetics
653 ## - INDEX TERM--UNCONTROLLED
Uncontrolled term Genetics and Molecular Biology
653 ## - INDEX TERM--UNCONTROLLED
Uncontrolled term Genomics
653 ## - INDEX TERM--UNCONTROLLED
Uncontrolled term Biochemistry
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Mohammad W. Khan
Relationship auth
856 40 - ELECTRONIC LOCATION AND ACCESS
Host name www.oapen.org
Uniform Resource Identifier <a href="https://www.intechopen.com/books/modulating-gene-expression-abridging-the-rnai-and-crispr-cas9-technologies">https://www.intechopen.com/books/modulating-gene-expression-abridging-the-rnai-and-crispr-cas9-technologies</a>
Access status 0
Public note DOAB: download the publication
856 40 - ELECTRONIC LOCATION AND ACCESS
Host name www.oapen.org
Uniform Resource Identifier <a href="https://directory.doabooks.org/handle/20.500.12854/53807">https://directory.doabooks.org/handle/20.500.12854/53807</a>
Access status 0
Public note DOAB: description of the publication

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